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Economic evaluation of treatments for Alzheimer's disease
(2003-11-14)
of care was simulated for a cohort of patients over a period of 5 years. In a linear regression model controlling for age and gender, a decrease by 1 point in MMSE score was associated with an increase in annual costs by 15 000 SEK.
Study II estimated...
Interventions for improved prescribing and dispensing of medicines in Nepal, Thailand and Vietnam
(2003-11-17)
: In the intervention groups: I: Attendance fell 18% the first year and recovered over 3 years. Items per prescription were 2.5 (1.7 in control and 1.4 calculated needed values). 61 % of prescriptions contained antibiotics (37% in control and 27% calculated needed value...
Evaluation of the deoxyribonucleoside kinase of Drosophila melanogaster (Dm-dNK) as a suicide gene for treatment of solid tumors
(2002-05-16)
Nucleoside kinases from several species are investigated as "suicide genes" for treatment of malignant tumors. The transfer of the gene encoding herpes simplex virus type-1 thymidine kinase (HSV-1 TK) into malignant cells and subsequent treatment...
Long term health-related quality of life among women with high-risk breast cancer receiving adjuvant high-dose chemotherapy : a comparison with the normal population
(2002-02-01)
The aims of the thesis were 1) to provide reference values for the EORTC QLQ-C30 in the general Swedish population, 2) to investigate effects of adjuvant high-dose treatment on health-related quality of life (HRQoL) among high-risk breast cancer...
Extrahepatic cytochrome P450s : relation to cancer susceptibility
(2003-09-19)
on Swedish postmenopausal women. We genotyped approximately 1 500 breast cancer cases, 690 endometrial cancer cases and 1 500 controls and calculated odds ratios and 95 percent confidence intervals from conditional logistic regression models. We found...
Sacroiliac pain-provocation testing in physiotherapy : time and force recording
(2004-08-27)
Introduction: Some of the tests used for examining pain arising from the
sacroiliac region are intended to provoke pain by using manually applied
forces. Previous reliability and validity studies of sacroiliac
pain-provocation ...
HLA predisposition to human papillomavirus induced cervical neoplasia : population based studies from the Västerbotten county in northern Sweden
(2001-08-08)
Infection with human papillomaviruses (HPV) types 16 and 18 is the major
cause of cervical neoplasia. Although a high proportion of cervical
cancers (CXCA) harbor HPV genomes, only a small number of women infected
with ...
Indoor environment and recurrent wheezing in young children
(2003-02-21)
/concrete slab foundation, compared with those living in buildings erected before 1940, OR 2.5 (1.3-4.8) and OR 2.5 (1.1-5.4). This was not primarily explained by differences in type of ventilation systems, measured ventilation rate, occurrence of house dust mite...
Nano-electrospray mass spectrometry for the analysis of neurosteroids and related molecules
(2003-03-10)
of 1 pg/µL. Information about steroid structure was obtained from collision-induced dissociation (CID) spectra of 1 ng of steroid sulphate, while characterisation of the sulphate ester group required only 3 pg of material. Unconjugated oxosteroids were...
Molecular characterisation of major allergens from mite (Lep d 2) and cat (Fel d 1)
(2004-05-14)
the understanding of the mechanisms underlying cat allergy and to obtain knowledge for new treatment strategies, we have solved the crystal structure of the most potent cat allergen, Fel d 1. The structure of Fel d 1 was determined by X-ray crystallography at 1.8 A...