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Experimental studies on endotoxin infusion in human : evaluation of pharmacological immunomodulation by adenosine and nicotinamide
(2003-11-14)
attenuated the endotoxininduced IL-6 response whereas there was no clear effect on the TNF-α response. After oral nicotinamide treatment, there was no effect on the inflammatory parameters (TNF-α, IL-6, IL-8, IL-10 levels or exhaled NO) at the maximum dose...
Molecular complexities of patched signaling in cancer development
(2004-05-21)
Basal Cell Cancer (BCC) is the most common cancer in the Western world. Although BCCs hardly ever metastasize, invasive growth may cause considerable local tissue destruction. BCCs mainly occur as sporadic tumors but can ...
The relation of blood pressure to dementia in the elderly : a community-based longitudinal study
(2004-01-09)
This doctoral thesis concerns a community-based, prospective study aimed
at investigating the complex relationship between blood pressure (BP) and
risk of dementia in a dementia-free cohort (n = 1301) aged >=75 years ...
Nasal airway nitric oxide : methodological aspects and influence of inflammation
(2004-04-02)
Nitric oxide (NO) is an endogenously formed free radical gas involved in numerous biological processes. In 1991 NO was discovered to be present in exhaled air of humans. Soon after, it was reported that the largest amounts ...
Dentin surface conditioning : the role of collagen in dentin bonding
(2001-12-28)
Preparation of dental cavities inevitably produces a thin layer of smear, which covers dentin and enamel surfaces. This smear layer, which is between 1 and 10 gm thick, consists of hydroxyapatite, denatured collagen and ...
An analysis of parents experiences and the caregivers role following the birth of a stillborn child
(2003-11-21)
and representing 31 stillborn children demonstrated the parents experience of the caregivers support four to six years after the stillbirth.The physicians roles, attitudes and advice were investigated in a nationwide study comprising 594 physicians...
Synthesis of heterocycles from anthranilic acid and its derivatives
(2004-05-07)
Anthranilic acid (2-aminobenzoic acid, Aa) is the biochemical precursor to the amino acid tryptophan, as well as a catabolic product of tryptophan in animals. It is also integrated into many alkaloids isolated from plants. ...
Local anesthesia for pain relief after surgery
(2001-11-16)
Postoperative pain is a common problem in spite of increased awareness
among patients and healthcare professionals. The prevailing practice is
still to administer opiates, which have a good painrelieving potential
but ...
Autoimmune markers in autoimmune diabetes
(2003-12-19)
Type 1 diabetes mellitus (T1DM) is an autoimmune disease, characterized by autoimmune mediated loss of insulin secreting Beta-cells. The disease is associated with certain HLA class 11 haplotypes. HLA DR3-DQ2 and DR4-DQ8 are positively while DQ6...
Temporomandibular joint involvement by systemic inflammatory disease with reference to pain modulation and joint tissue destruction
(2003-11-07)
Systemic inflammatory diseases may cause progressive destruction in the temporo-mandibular joint (TMJ). Involvement of this joint is associated with many clinical signs and symptoms of which pain is a major problem. This ...