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Molecular genetic aspects of renal cell carcinoma development
(2003-04-25)
Renal cell carcinoma (RCC) is the most common tumor of the renal parenchyma. The aim of this study was to further characterize known as well as new genetic abnormalities in a clinical material of RCC, as well as in established ...
Molecular mechanisms underlying the glucose-dependent transcription of the insulin and glucokinase genes in the pancreatic beta-cell
(2002-03-27)
Background: Insulin is of vital importance in the maintenance of the glucose homeostasis in mammals. This necessitates a tight regulation of both insulin release and biosynthesis. Although pancreatic beta-cells secrete ...
Synthesis of heterocycles from anthranilic acid and its derivatives
(2004-05-07)
products were more or less complex 1,3-benzoxazinones, one of which required X-ray crystallography confirm its structure. During the work on preparation of N-substituted derivatives of Aa, necessary for synthesis of 1,4-benzodiazepine-3,5-diones...
Digital intraoral radiography : determination of technical properties and application evaluations
(2002-05-03)
function approximately compensates for the exponential attenuation of x-rays, as radiographs are exposed. The consequence of this compensation is, that equal steps in object thickness are shown with approximately equal steps in light intensity on a computer...
Intoxication of mammalian cells by the cytolethal distending toxin of Haemophilus ducreyi : a novel mechanism of action
(2001-09-14)
The cytolethal distending toxins (CDTs) are a newly described family of
bacterial protein toxins with a novel mechanism of action: DNA damage.
Haemophilus ducreyi produces a cytotoxin that belongs to this family.
This ...
Genetic studies of hypospadias
(2002-11-22)
with low birth weight in 2138 families with at least one boy with hypospadias. There was a familial rate of 7% and a significant lower birth weight in cases with hypospadias compared with their respective brothers, used as controls (p=5x10-13). An increased...
Biocomputational studies on protein structures
(2002-08-16)
Biology in the post-genomic era produces large amount of data. This, in combination with the need for efficient algorithms to find genes in the genomic material, has brought a renaissance into the field of computational ...
Morbidity in Ménières disease : aspects on quality of life and triggering factors
(2002-11-22)
Menieres disease is an inner ear disorder of unclear origin, characterized by severe attacks of simultaneously appearing fluctuant hearing loss, vertigo, tinnitus and a feeling of aural fullness. The disease has a well-known ...
Physical performance tests and spinal pain : assessing impairments and activity limitations
(2002-05-09)
Background: Long-term spinal pain is a common health problem, often leading to disabilities. There is still no general agreement on what measures to use for evaluating disability in people with spinal pain. Performance-based ...
Intestinal functions in animals : an experimental study on horses, pigs, cows and fish
(2001-11-07)
Animals and humans live in symbiosis with an active gastrointestinal
ecosystem. The balance of the system is maintained by the main actors,
the macroorganism, the microflora and the environment, in concert.
Microflora ...