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Pain-related fear and movement : implications for physiotherapy and public health
(2003-01-17)
Long-term musculoskeletal pain is a large public health problem with serious consequences both for the individual and society. Fear-avoidance beliefs and catastrophizing are powerful cognitions in the process of developing ...
Genetic dissection of multifactorial disease models in the rat
(2002-08-26)
weight. The first genome-wide scan with 253 markers revealed three glucose-related loci, Niddm I (LOD 11), Niddm2 (LOD 4.5) and Niddm3 (LOD 4.6), and one locus, Weight1 (LOD 6.2), for body weight on chromosomes 1, 2, 10, and 7 respectively, supporting...
Implantable devices in heart failure : studies on biventricular pacing and continuous hemodynamic monitoring
(2002-09-13)
on functional status and quality of life (QoL) in 16 patients with NYHA III-IV heart failure. After 6 months of biventricular pacing, NYHA-class, the 6-minute walking distance and QoL had improved significantly. This clinical improvement translated into a marked...
Genetic studies of atopic dermatitis
(2001-11-22)
q35, 3q21, 5q31, 6p21, 11q13, and 14q11), previously implicated as candidate regions in atopic, diseases, and one new candidate gene, the gene for Wiskott-Aldrich syndrome located on Xp 11. These candidate genes were investigated in 572 affected sib...
Birth centre care : reproduction and infant health
(2004-04-02)
This thesis has two general aims, to investigate factors affecting
women s decision to have a second baby and to study the effect of birth
centre care on infant outcome. The specific aims were to investigate 1)
whether ...
Skin cancer prevention : behaviours related to sun exposure and early detection
(2003-09-05)
Skin cancer is an emerging public health problem in Sweden. Even though the most important risk factor for the development of skin cancer - sun exposure - is known, the incidence of skin cancer is still increasing. Every ...
Strategies of gene and immune therapy for tumors and viral diseases
(2003-04-04)
In the treatment of tumors and viral diseases such as HIV-1 infection, immunotherapeutic strategies do not seem to have enough capacity to eradicate an already established disease. However, these strategies could play a ...
Nano-electrospray mass spectrometry for the analysis of neurosteroids and related molecules
(2003-03-10)
not detected at levels above the detection limit, 0.3 ng/g wet brain, while pregnenolone sulphate, added to brain extract at a level of 6.6 ng/g, was easily detected. The unconjugated oxosteroids were converted to their oximes, selectively isolated on a cation...
Nuclear hormone receptors studied by molecular dynamics computer simulations
(2004-03-05)
Nuclear hormone receptors form a super family of homologous transcription factors. The liganddependent nuclear receptors are important drug targets controlling metabolic and inflammatory disorders, amongst others. The ...
Diabetic osteopathy : a study in the rat
(2012-03-09)
The present study on non-obese Goto-Kakizaki (GK) rats with type-2 diabetes and neuropathy was an attempt to describe and define pertinent features of diabetic osteopathy. Altogether, the study included 33 GK rats aged 12 ...