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T-cell competition as a mechanism for immunodominance and the role for IL-12 in CTL responses
(2002-11-15)
Immunodominance is a process in which the immune response focuses on one
or a few of all potential epitopes that exists within an antigen. The
mechanisms for immunodominance have not yet been determined. The work
described ...
Sudden infant death syndrome : a medico-legal study of related cardiovascular, toxicological and genetic findings
(2002-05-03)
pathology (including heart weight,
malformations and myocarditis); exposure to nicotine; and mutations
and/or polymorphisms in mitochondrial DNA (mtDNA). A total of 505 infants
investigated at the Department of Forensic Medicine in Stockholm, between
1980...
Hypothalamic neuronal circuits involved in the regulation of food intake and body weight : histochemical studies in lean rats and obese mutant mice
(2004-01-09)
Obesity is a major health problem because of its dramatic increase in
prevalence and its association with type 2 diabetes, coronary heart
diseases, hypertension and stroke. It is well known that signals
generated in ...
Vibro cholerae O139 : identification, characterization and vaccine strategies
(2003-10-24)
Cholera is an acute dehydrating diarrheal disease, and epidemics as well as pandemics of cholera are a major health problem in developing countries and cause many deaths each year, especially in children. Cholera is caused ...
Role of protein-tyrosine phospatases in insulin and glucagon secretion in pancreatic islets of healthy rats and spontaneously diabetic GK rats
(2004-03-26)
. At 3.3 mM glucose, 0.1-1 mM pV stimulated insulin secretion (p<0.05), while at 16.7 mM glucose 0.01-0.1 mM pV inhibited its secretion (p<0.05). These effects were not mediated by pV modulation of islet glucose metabolism, or by interference with Gi...
Birth centre care : reproduction and infant health
(2004-04-02)
This thesis has two general aims, to investigate factors affecting
women s decision to have a second baby and to study the effect of birth
centre care on infant outcome. The specific aims were to investigate 1)
whether ...
Diabetic osteopathy : a study in the rat
(2012-03-09)
The present study on non-obese Goto-Kakizaki (GK) rats with type-2 diabetes and neuropathy was an attempt to describe and define pertinent features of diabetic osteopathy. Altogether, the study included 33 GK rats aged 12 ...
Minimally invasive hernia surgery
(2003-04-25)
/inflammations, including intestinal obstruction, 58.99. The RR was 2.79 with TAPP and 0.57 with TEP compared to Lichtenstein operated patients....
Cholangiocarcinoma in primary sclerosing cholangitis
(2001-10-05)
, laboratory or radiological findings. The number of patients being either current or former smokers was significantly higher in the cancer group than among controls (p<0.0004). To analyse the concept of bile duct dysplasia and the possibility of agreement...
Synthesis of heterocycles from anthranilic acid and its derivatives
(2004-05-07)
Anthranilic acid (2-aminobenzoic acid, Aa) is the biochemical precursor to the amino acid tryptophan, as well as a catabolic product of tryptophan in animals. It is also integrated into many alkaloids isolated from plants. ...