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Biophysical aspects of contact dermatitis and its prevention
(2004-03-05)
The skin, one of the largest organs of the body, is composed of three layers: the epidermis, dermis and subcutis. The outer most part of the epidermis i.e., the stratum corneum - serves as a protective barrier between the ...
Crystallographic studies of enzymes involved in biosynthesis of fatty acids : beta-ketoacyl-acyl carrier protein synthase II and delta9-stearoyl-ACP desaturase
(2003-05-16)
In the biosynthesis of fatty acids, the beta-Ketoacyl Acyl Carrier Protein Synthases (Kas) catalyse chain elongation by the addition of two-carbon units derived from malonyl-ACP, to an acyl group bound to CoA or the small ...
On the clinical value of genetic analysis in colorectal cancer patients
(2003-11-14)
, LOH at 5q could not be detected. The frequency of LOH-positive biopsies varied widely within the tumors. In contrast, k-ras mutations were found to occur practically in all biopsies throughout the tumours in 7/17 (41%) and not at all in 9/17 (53%). Our...
Alexithymia : background and consequences
(2002-03-04)
from 1.8% to 11.7% after the investigation in paper 11. Patients with undetected depression scored higher on alexithymia and psychastenia. In the study in occupational health the prevalence of alexithymia was 7.9% in the all-female population. We found...
Gender perspectives on psychosocial risk factors : conditions governing women's lives in relation to stress and coronary heart disease
(2003-05-02)
The overall aim of this thesis was to shed light on womens psychosocial perceived stress as it is shaped within a gender-structured reality. By using a gender theoretical and social psychological approach the thesis aims ...
The treatment of depression in clinical practice : a public health perspective
(2004-05-14)
been an increase in the use of antidepressant drugs, the prevalence of their reported use among depressed individuals is between 7% and 19.7%. The principal aim of this project was to investigate the evidence for the rational use of antidepressant...
Modelling biomolecular interactions
(2003-05-16)
Computational approaches for understanding and aiding in molecular biology has increased in significance over the last decades, where a wealth of biochemical experiments have provided a solid ground for developing computer ...
Local recurrence after breast conserving surgery in breast cancer
(2002-08-30)
The general aim of this thesis was to gain increased insight into the problem of local recurrences after breast conserving surgery for breast cancer. In a population-based cohort of 4,694 women with invasive breast cancer, ...
Severe hypoxemia during apnea in humans : influence of cardiovascular responses
(2002-09-13)
When a diving human holds his or her breath, the heart beat slows and the blood vessels constrict in large portions of the body. In diving mammals such as seals, similar responses effectively conserve oxygen for the brain, ...
Minimally invasive hernia surgery
(2003-04-25)
Lichtenstein (5 vs. 7 days). The time of rehabilitation was shorter after TEP than mesh-plug or Lichtenstein (14 vs. 24.5 vs. 28.5 days). There was a tendency of more pain after Lichtenstein than after TEP or mesh-plug at follow-up. Laparoscopic hernioplasty...