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Imaging of soft tissue tumors
(2003-09-19)
The aim of this project on soft tissue tumors, was to evaluate existing imaging methods and test new Magnetic Resonance Imaging (MRI) sequences for diagnosis and assessment of cytotoxic therapy and to relate the imaging ...
Studies on oxysterols : origins, properties and roles
(2003-09-05)
Oxysterols are derivatives of cholesterol present at low concentrations in a variety of physiological compartments. The major oxysterols in human circulation are formed from pools of cholesterol that may be distinguished ...
Determinants of ligand-induced nuclear receptor activation
(2004-05-13)
. Based on structural and mutational studies, we suggest that the observed hydrogen bonds with His421 and Trp443 serve as the molecular basis for ligand dependent activation of LXRs. Further, the absence of interaction between helix 12 of LXR and amino...
Significance of polymorphisms in human xenobiotic metabolising enzymes
(2002-12-20)
Cigarette smoke is the primary cause of lung cancer but urban air pollution and certain occupational exposures have also been found to elevate the incidence of lung cancer. These exposures contain polycyclic aromatic ...
Effects of influenza A virus infections and interferon-gamma on synapse formation and function in hippocampal neurons in culture
(2004-09-03)
The central nervous system (CNS) can be the target for several infections that include those with RNA viruses. The parenchyma of the CNS is considered an immuneprivileged site since it is protected behind the blood-brain ...
Some determinants of sick leave for respiratory disease : occupation, asthma, obesity, smoking and rehabilitation
(2002-09-20)
to
be an underreported diagnosis, approximately by a factor of three. In the
study of obesity in paper III the prevalence of obesity in asthmatics on
sick leave was 20.7%, compared with 13.7% in the non-specific pain
patients on sick leave and in 6.5% of a random general...
Women’s expectations and experience of care during pregnancy and childbirth
(2003-10-03)
breast-feeding and infant care and the ability to participate in parent education classes. Paper (II): The aim was to follow up the number of antenatal visits and women’s opinions of the number of visits and satisfaction with antenatal care. In all, 2,421...
Rehabilitation in a changing context : responses, difficulties and competence from the view of occupational therapists and clients : consequences of the ideological and organisational changes in psychiatry
(2003-05-23)
The general aim of this thesis was to explore, understand and describe how occupational therapists have responded to the consequences of the ideological and organizational changes in psychiatry that have taken place in ...
Dendritic cells in the development of antimicrobial immunity : studies on Epstein-Barr virus and the Haemophilus ducreyi cytolethal distending toxin
(2002-05-16)
Dendritic cell (DC) plays a pivotal role in both innate and adaptive immunity, we studied the inhibitory effect of pathogens on the development and maturation of monocyte derived DCs, with special emphasis on the effect ...
Synthesis of heterocycles from anthranilic acid and its derivatives
(2004-05-07)
Anthranilic acid (2-aminobenzoic acid, Aa) is the biochemical precursor to the amino acid tryptophan, as well as a catabolic product of tryptophan in animals. It is also integrated into many alkaloids isolated from plants. ...