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Equity and equality : case detection of tuberculosis among women and men in Vietnam
(2003-05-02)
sputum smear-positive TB cases. Currently global case detection is estimated to 40% of an approximated 8.74 million new sputum smear-positive pulmonary TB cases yearly. Vietnam, a high-burden TB country, reports to have reached 80% case detection. About 2...
Helicobacter pylori eradication in the Swedish population
(2017-04-28)
decreased over the study period. Overall, 91.0% had 1 eradication and 0.1% had more than 3. Of all eradications, 95.4% followed the recommended regimen, while 4.7% did not. The latter group was overrepresented among individuals aged ≥80 years (7.8...
Regulation of skeletal muscle metabolism and development by small, non-coding RNAs : implications for insulin resistance and type 2 diabetes mellitus
(2018-05-23)
microRNAs (miRNAs) are a class of epigenetic post-transcriptional regulators. These short (~22 nucleotides) non-coding RNAs can potently reduce protein abundance through direction of the RNA-induced silencing complex to ...
MicroRNAs in skin immunity and psoriasis
(2014-12-16)
The skin protects the organism from the environment and shields it from the constant danger of infections by microorganisms. Keratinocytes are epithelial cells in the skin that constitute a physical barrier towards the ...
Emerging roles of PFKFB3 and CX3CR1 in the DNA damage response and their potential as therapeutic targets in cancer
(2021-06-01)
Genomic instability in cancer is exploited therapeutically using DNA damaging therapies that cause irreparable lesions above the threshold of tolerable DNA damage levels. Nevertheless, toxic side effects on healthy tissues ...