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Galanin and Leu-enkephalin in the rat : with special reference to adjuvant arthritis
(2004-05-20)
In these studies, the tissue and cellular distribution of Galanin and
Leu-enkephalin were demonstrated in normal bone and joints. Furthermore,
tissue levels of Galanin and Leuenkephalin were also studied in the
ankles ...
Description and prediction of clinical radiosensitivity : emphasis on normal tissue reactions
(2004-02-27)
on sensitivity of the thyroid and the lung to RT.
RT of head and neck cancer frequently involves the thyroid gland and can
cause thyroid dysfunction. The thyroid function was prospectively studied
in a cohort of 391 patients with head and neck cancer admitted...
Cytochrome P450 2C9, 2C19 and 2D6 genetic polymorphisms : evaluation of genotyping as a tool for individualised treatment
(2003-01-03)
Recent advances in the understanding of drug metabolism and the molecular biology of CYPs have generated great expectations regarding the use of pharmacogenetic testing as a tool to individualize drug treatment. The ...
SNP based strategies to study candidate genes for Alzheimer’s disease
(2002-11-08)
Alzheimer’s disease (AD) is the most common form of dementia in the elderly. It is a genetically heterogeneous disease characterized by progressive cognitive decline and memory impairment. The rare familial form of AD is ...
Enzymatic mechanisms in biotin synthesis : vitamin B6 catalysis and phosphoryl transfer
(2003-08-15)
With the large number of pathogenic bacteria that have developed antibiotic resistance it is increasingly important to find new targets for antibiotics. Our interest in the biotin biosynthesis pathway originates from this ...
Local recurrence after breast conserving surgery in breast cancer
(2002-08-30)
The general aim of this thesis was to gain increased insight into the problem of local recurrences after breast conserving surgery for breast cancer. In a population-based cohort of 4,694 women with invasive breast cancer, ...
Minimally invasive hernia surgery
(2003-04-25)
/inflammations, including intestinal obstruction, 58.99. The RR was 2.79 with TAPP and 0.57 with TEP compared to Lichtenstein operated patients....
Lumbar muscle fatigue and recovery : evaluation of electromyography in patients with long-term low-back pain and in healthy subjects
(2002-11-22)
was somewhat higher for patients (ICC>0.6) than for healthy subjects. The initial median frequency and, to a greater extent, the slope were sensitive to the exerted torque. The patients differed from the healthy subjects by lower MVC torque, higher initial...
Synthesis of heterocycles from anthranilic acid and its derivatives
(2004-05-07)
Anthranilic acid (2-aminobenzoic acid, Aa) is the biochemical precursor to the amino acid tryptophan, as well as a catabolic product of tryptophan in animals. It is also integrated into many alkaloids isolated from plants. ...
The biological mechanisms in neutrophil and eosinophil adhesion and transmigration in vitro and theur relation to the inflammatory process in vivo
(2001-12-28)
In inflammatory reactions, eosinophils and neutrophils constitute the
major classes of granulocytes that emigrate from the bloodstream into the
tissues. The recruitment of inflammatory cells constitutes a multi-step
process ...