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Undergoing stem-cell transplantation : patients perceptions of symptoms, functional status and health-related quality of life
(2002-05-24)
was suffering from. From the day of the stem-cell infusion (T2) and up to approximately 10 days after the transplantation (T5), between 33 % and 54% of the patients reported > 10 simultaneous symptoms. Tiredness (81-91%), loss of appetite (88-93%) and mouth...
Molecular cloning and characterization of the murine acyl-CoA thioesterase CTE-I
(2004-04-23)
Mouse cytosolic type I acyl-CoA thioesterase (CTE-I) is a member of the
type I family of acylCoA thioesterases. These enzymes hydrolyze acyl-CoAs
to non-esterified fatty acids (NEFAs) and Coenzyme A (CoA-SH) and are
strongly ...
Molecular dynamics studies of water and biomolecules
(2002-05-24)
This thesis concerns different areas of molecular dynamics (MD) simulations. In the first part of the thesis the ability of liquid water models to mimic the real bulk water properties and the accuracy of the methods to ...
Sarcoidosis : inflammatory mechanisms and markers of activity
(2002-10-25)
Sarcoidosis is a disease characterized by an accumulation of CD4+ T-lymphocytes in affected organs. Previous findings of an association between the HLA-allele DR17 and an accumulation in bronchoalveolar lavage fluid (BALF) ...
Coagulation and inflammation in experimental endotoxemia in vitro and in vivo : monitoring method and effects of nicotinamide
(2003-03-07)
In gram negative sepsis, endotoxin from the bacterial membrane elicits proinflammatory and procoagulant host responses. Sepsis and its frequent complication disseminated intravascular coagulation (DIC) are leading causes ...
Combined radiology and cytology in the diagnosis of bone lesions : a study of 494 patients
(2002-11-22)
diagnosis was given by the cytologists in 22 and 23 cases, respectively, incorrect in 2 and non-conclusive in 5 and 4. The study suggests that true tumour heterogeneity is rare. The interobserver difference and diagnostic difficulties should mainly...
Medical interventions and gastric cancer risk : an observational approach
(2004-05-14)
treatment (OR, 0.7 95% Cl, 0.5- 1. 1) conferred a
reduction in gastric cancer risk.
To further test the hypothesis that exposure to heavy antibiotic
treatment reduces the risk of gastric cancer, we assessed cancer risk
among 336,017 patients hospitalized...
Gait in patients with knee osteoarthritis : effects of preoperative physical therapy and two surgical interventions
(2004-09-16)
: Study I. Thirty-four patients were randomised to a preoperative
physical therapy exercise programme during 5 weeks before surgery while
34 patients received no treatment. Outcome measures were: Patient's
opinion of knee functioning, pain during walking...
Postoperative nausea and vomiting in women : an unglamorous aspect of anaesthesia
(2002-08-23)
anaesthetic regimens were studied with respect to the incidence of PONV and to identify potentially favourable anaesthetic combinations with regards to PONY The antiemetic effects of the 5-HT3 receptor antagonist tropisetron, intra-operative positive...
Ventricular repolarization in the human heart : effects of pharmacological and non-pharmacological interventions
(2001-11-02)
Ventricular arrhythmias is the main cause of sudden cardiac death. A
prolonged repolarization might cause such arrhythmias, and an increased
understanding about mechanisms is therefore important for their primary
and ...