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Stiffness changes of the tympanic membrane in otitis media
(2002-05-03)
Acute purulent otitis media and otitis media with effusion, are common
diseases in childhood. Years later some of the children will get
"complications", such as retraction pockets and cholesteatoma, that often
need advanced ...
Glucocorticoids in the development and homeostasis of T lymphocytes
(2002-05-24)
young and aged mice. In addition, these suppressive effects were more pronounced on CD4+ T cells, resulting in a decreased CD4+:CD8+ T cell ratio.
Taken together, our results demonstrate that endogenous GCs at physiological non-stressed levels...
Structural studies of bacterial carbohydrate antigens with focus on oral commensal bacteria
(2002-08-15)
90% of the total number of cells in the human body consist of the normal
bacterial flora. These bacteria are mostly not harmful and, indeed, even
beneficial as long as they remain physiologically outside the body, e.g.,
within ...
Atherosclerosis of the ascending aorta as a risk factor for stroke after cardiac surgery : a study based on epiaortic ultrasound
(2004-04-23)
% of the ascending aorta diseased and those with more than 50% affected
were 95.3±0.9%, 91.8±2.1% and 65.0±14.6%, respectively (p<0.0001). The
distal-left side of the ascending aorta was associated with a 5-fold
increase in 5-year stroke rate.
Conclusions...
The social patterning of road traffic injuries during childhood and youth : national longitudinal register-based studies
(2004-05-07)
of the household is studied in
relation to hospital-based road traffic injuries as pedestrians,
bicyclists, moped-riders, motorcyclists and car drivers, for the period
19871994 (when subjects were aged 2-24 years). Morbidity differences
between groups are observed...
Experimental design of phenotyping probe drugs with emphasis on CYP1A2 : their use in studies on genetic and environmental regulation of drug metabolism
(2003-05-02)
=0. 82) and the urinary ratio of N-3-demethylated metabolites / caffeine collected for 8 or 24 hours (rs=0.63-0.70). The use of a 36-hour caffeine abstinence period was appropriate to avoid the influence of caffeine ingested before the study...
CTLA-4 expression, regulation and associations in autoimmune myasthenia gravis
(2003-10-17)
Myasthenia gravis (MG) is a neuromuscular disease with muscle weakness due to an autoimmune attack against the nicotinic acetylcholine receptor (nAChR) on the skeletal muscle endplate. Cytotoxic-T-lymphocyte-associated ...
Molecular markers and new techniques in the evaluation of colorectal cancer
(2002-05-17)
Colorectal cancer (CRC) is ranked in the Western world as the third leading cause of death from malignant tumors. Despite improvements in early detection of the disease, new surgical techniques and adjuvant and neoadjuvant ...
Welander distal myopathy : gene mapping and analysis of candidate genes
(2004-03-04)
Distal myopathies constitute of a very heterogeneous group of muscular
disorders. Distal myopathies have previously been classified according to
features such as; clinical symptoms, age of onset and histopathological
changes. ...
Synthesis of heterocycles from anthranilic acid and its derivatives
(2004-05-07)
Anthranilic acid (2-aminobenzoic acid, Aa) is the biochemical precursor to the amino acid tryptophan, as well as a catabolic product of tryptophan in animals. It is also integrated into many alkaloids isolated from plants. ...