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Cognitive functioning in aging and dementia : the role of psychiatric and somatic factors
(2002-05-24)
This doctorial thesis concerns the role of psychiatric and somatic factors in aging and dementia. Five studies are included, all based on data from the Kungsholmen Project, a population-based longitudinal study of aging ...
Acquisition and function of NK cell-associated molecules on T cells
(2003-03-21)
One challenge for multicellular organisms, including humans, is to cope with a broad variety of microorganisms and their rapid replication and alterations. To do this, both fast and specific defense mechanisms are needed ...
Endemic ataxic polyneuropathy in Nigeria
(2002-03-22)
in gari during storage were studied.
The prevalence of ataxic polyneuropathy was 490 per 10 000 in Ososa compared with 17 per 10 000 in Jobele. The age standardised prevalence ratio between Jobele and Ososa was 4 % (95 % Cl 0 - 9). The incidence...
Hazardous or harmful alcohol use in emergency care : early detection, motivation to change and brief intervention
(2003-05-21)
Alcohol often leads to accidents, assaults, poor health in the family and is associated with psychiatric and somatic diseases. Binge drinking, in particular, has been shown to be a central factor in alcohol related problems. ...
Tracer development and PET studies : labeled proinsulin C-peptide and an EGFR-TK inhibitor
(2002-05-17)
Positron emission tomography (PET), which localizes and quantifies
positron decays over time, enables non-invasive in vivo distribution
studies of trace amounts of compounds labeled with positron emitters. The
use of ...
Approaches for the localization and identification of human cancer genes
(2002-09-18)
and MEN2-related pheochromocytomas.
In the series of 23 cases of SCLC analyzed, CGH alterations were frequently detected ranging from 9 to 22 changes in the individual tumors, suggesting the malignant phenotype of this tumor type. The identification...
Population-based studies of body mass index, overweight and systolic blood pressure among Swedish young men
(2002-08-30)
Overweight and obesity has increased in Sweden and worldwide in recent decades. Lifestyle and environmental changes, genetic susceptibility and interactions between these factors are believed to be important. A theoretical ...
Functional properties of antibodies in resistance against HIV-1 infection
(2002-02-22)
During the last years a few populations who remain uninfected despite repeated HIV-1 viral exposures have been described. Several mechanisms were suggested to be associated with this natural resistance including HIV-1-specific ...
Neurochemical and behavioral studies on ethanol and brain opiod interactions in the brain
(2001-09-28)
Substance dependence is a devastating disorder that produces enormous socio-economic costs, personal tragedies and health related problems. The brain mesolimbic dopamine pathway originating in the ventral tegmental area ...
Immunological studies in the brain and signaling pathways in experimental African trypanosomiasis
(2001-11-23)
African Trypanosomiasis is a disease prevalent among humans and animals in tropical Africa which is caused by the extracellular hemoflagellate Trypanosoma brucei (T. b.). The infection is initiated when a tsetse fly commences ...