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Managers working conditions : stress and health
(2002-05-16)
Stress and stress related diseases have increased during the recent years. Managers exert influence on employees and consequently managers' stress and health impact on the subordinates as well as on themselves.
There ...
Oxidative stress and calcium signalling : implications for diabetes and cardiac glycosides
(2003-05-23)
The signal transduction processes by which an individual cell is able to recognize and respond to its external environment are critical to determining its survival as well as that of the entire organism. In the current ...
Ligand-receptor interactions and signaling cross-talk in the TGF-b superfamily
(2003-01-31)
involved in signaling through the receptor activin receptor-like kinase 7 (ALK7). ALK7 is a type I receptor with a specific expression pattern in the nervous system, pancreas and brown fat. At the time the present work commenced, the cognate ligand, type II...
Pulmonary tuberculosis and HIV interaction in a setting with a high prevalence of HIV : clinical, diagnostic and epidemiological aspects
(2002-05-17)
increased the yield for AFB, suggesting did this method has a place m routine diagnosis of PTB m HIV endemic countries. Molecular strain typing of the IS6110 and direct repeat genetic markets and drug sensitivity testing were performed in 121 M tuberculosis...
Genetic dissection of multifactorial disease models in the rat
(2002-08-26)
weight. The first genome-wide scan with 253 markers revealed three glucose-related loci, Niddm I (LOD 11), Niddm2 (LOD 4.5) and Niddm3 (LOD 4.6), and one locus, Weight1 (LOD 6.2), for body weight on chromosomes 1, 2, 10, and 7 respectively, supporting...
On associations between different factors and whiplash injury
(2002-01-04)
was estimated according to a mailed questionnaire at follow-up in 1994, 7 years after the rear-end collision. The age- and gender-adjusted relative risk (RR) of health complaints at follow-up was calculated for subjects in each exposed subgroup as compared...
Molecular genetics of type 2 diabetes
(2002-04-24)
on rat chromosomes 1, 5, and 10.
Seven gender-influenced QTLs significantly affecting diabetes were assigned to chromosomes 1, 2, 5, 7, 10, and 18 with LOD scores > 4.0. These findings indicate that hyperglycemia, body weight, and insulin resistance...
Aspects of gastroesophageal reflux and risk for esophageal cancer : an epidemiological approach
(2003-10-24)
selected controls. We also followed 21,265 patients hospitalized for pernicious anemia in Sweden between 1965 and 1999 for an average of 7.1 years and estimated relative risks of esophageal cancer by histology. Finally, polymorphisms in XPD codon 751 (Lys...
On the clinical value of genetic analysis in colorectal cancer patients
(2003-11-14)
, LOH at 5q could not be detected. The frequency of LOH-positive biopsies varied widely within the tumors. In contrast, k-ras mutations were found to occur practically in all biopsies throughout the tumours in 7/17 (41%) and not at all in 9/17 (53%). Our...
Posterior ocular malformations in children : teratological aspects
(2003-05-16)
Posterior ocular malformations are common causes of visual impairment in Swedish children. The most frequent diagnoses within this group are optic nerve hypoplasia and optic nerve/chorioretinal coloboma. Genetic factors, ...