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Parasite signalling and host responses in experimental and human African trypanosomiasis
(2002-08-08)
African trypanosomiasis or sleeping sickness is a disease of tropical Africa caused by the unicellular-flagellated protozoan parasite, Trypanosoma brucei (T b.), which is transmitted by its insect vector, the tsetse fly. ...
Nitric oxide in inflammatory bowel disease
(2003-08-15)
The aim of this study was to study nitric oxide (NO) in inflammatory bowel disease (IBD) with a special reference to disease activity and disease location, in bolls an adult and a pediatric patient population, using rectal ...
Nestin regulation in the embryonic and adult CNS
(2001-11-09)
/progenitor cells, including early neural crest cells, in the developing CNS. A 120-bp long region in the 374-bp element is absolutely required for the pan-neural CNS expression, as deletion of the 120-bp region resulted in the retention of expression only in a...
Genetic dissection of multifactorial disease models in the rat
(2002-08-26)
, four major parent-of-origin-specific QTLs were uncovered, implicating potential importance of mitochondrial and/or epigenetic effects in the GK rat. Niddm4, a major locus on chromosome 9 affected fasting insulin paternally (LOD 6.9 in F2F344 rats vs. 0...
Atrial fibrillation : clinical managements with special emphasis on cardioversion
(2002-08-23)
the hypotheses that one high-energy shock is more efficacious than incremental shocks, 120 consecutive patients referred for a first elective cardioversion were randomized to one shock of 360 J or incremental shocks starting at 100 J with a stepwise increase...
Studies of leukotriene C4 synthase isoenzymes and the cysteinyl leukotrine receptors in human endothelial- and mast cells
(2003-09-19)
), showed a transient up-regulation of LTC4S mRNA within one hour in almost all tissues. LTC4S protein expression in brain, heart, liver, and adrenal gland increased 4.9-, 4.0, 2.9- and 2.3-fold, respectively. No effects were detected for MGST 2 or -3...
Effects of bacterial toxins on calcium homeostasis in renal inflammation
(2004-04-23)
-dependent effect where high concentrations caused elevated levels of Ca 2+ followed by cell lysis, whereas sub-lytic concentrations induced intracellular Ca2+ oscillations. Spectral analysis revealed that oscillations occurred with a periodicity of 12.0 ± 0.7 min...
The elite cross-country skier : clinical and sports related functional tests, dance training, injuries and self-related health
(2003-03-14)
The general aim of this thesis was to study cross-country skiers regarding the effect of dance training on joint mobility and muscle flexibility of the spine, hip and ankle and on speed and agility. Another aim was to ...
Blood pressure in acute ischaemic stroke : blood pressure and stress in the acute phase of stroke and influence of initial blood pressure on stroke-outcome
(2003-11-07)
(>160/90 mm Hg) had a poor functional outcome (combined death or dependency) at 21-days compared to patients with normal initial BP (120-160/60-90 min Hg). Patients with low initial BP (<120/60) also had a poor functional outcome compared to patients...
Functional properties of antibodies in resistance against HIV-1 infection
(2002-02-22)
, in the sixth paper we analyzed the capacity of two human monoclonal antibodies to inhibit HIV-1 transcytosis across a human intestinal epithelial cell line. Both gp120 V3 binding Mabs exhibited the capacity to limit the transcytosis of a T-cell laboratory...