Search
Now showing items 1-10 of 23
Synthetic development towards benzodiazepine alkaloids : total synthesis of circumdatin F and C
(2001-12-31)
Benzodiazepine alkaloids exhibit a multitude of interesting pharmacological activities. This thesis deals with the development of synthetic methods towards such alkaloids, of which the main efforts can be divided into three ...
Peptidergic innervation of periarticular tissue : a study in the rat
(2001-11-16)
Painful musculo-skeletal disorders pose a tremendous burden on the
healthcare system, the main reason being the limited knowledge of the
underlying pathomechanisms and lack of specific treatment.
Hypothetically, the ...
Natural and induced idiotype immunity in patients with multiple myeloma
(2004-02-20)
/elimination of circulating clonal tumor B cells were analyzed during Id immunization with real-time, allele-specific oligonucleotide (ASO) polymerase chain reaction (PCR). Among 6 evaluable patients, 4 displayed 54-100% reduction of circulating clonal B cells during...
Clinical application of QLF and DIAGNOdent : two new methods for quantification of dental caries
(2002-02-25)
lesions over a period of 6 months in a randomised, controlled study. In Paper IV, the QLF method was tested for intra- and inter-operator reliability in vivo for the capturing part as well as the image analysis part of the method. In Paper III, Ka...
Birth centre care : reproduction and infant health
(2004-04-02)
This thesis has two general aims, to investigate factors affecting
women s decision to have a second baby and to study the effect of birth
centre care on infant outcome. The specific aims were to investigate 1)
whether ...
Tissue destruction in arthritis : experimental studies
(2003-11-14)
Destruction of joint cartilage and bone is one of the most serious consequences of chronic arthritis. Clinically, the standard assessment of joint destruction is performed by radiography. The sensitivity of radiographic ...
Minimally invasive hernia surgery
(2003-04-25)
Minimally invasive laparoscopic and open tension-free techniques have been evolved during the 1990's. Different laparoscopic techniques have been used, where the totally extraperitoneal hernioplasty (TEP) is a technically ...
Autoimmune markers in autoimmune diabetes
(2003-12-19)
Type 1 diabetes mellitus (T1DM) is an autoimmune disease, characterized by autoimmune mediated loss of insulin secreting Beta-cells. The disease is associated with certain HLA class 11 haplotypes. HLA DR3-DQ2 and DR4-DQ8 are positively while DQ6...
Quality of life in patients with malignant blood disorders : a clinical and methodological study
(2002-10-25)
The overall aim of this thesis was to evaluate and, improve measurements of, health-related quality of life (HRQL) in patients with malignant blood disorders. Patients undergoing autologous stem cell transplantation (SCT), ...
Lower limb ischemia in women
(2004-02-27)
Arteriosclerosis is a general disease affecting different parts of the arterial system. In coronary heart disease (CHD) women have different risk factors, symptoms, indication for treatment, interpretation of diagnostic ...