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The structural diversity of lipopolysaccharides expressed by genetically defined clinical isolates of nontypeable Haemophilus influenzae
(2003-08-08)
Nontypeable Haemophilus influenzae (NTHi) is an important cause of otitis media and respiratory tract infections. Its lipopolysaccharide (LPS) molecule, an outer membrane component, is a major virulence factor of NTHi. The ...
Ultraviolet radiation and cornea
(2002-03-01)
Background: Acute exposure of the mammalian eye to UVR results in development of photokeratitis after a period of a few hours. Chronic exposure to UVR is associated with an increased risk of several corneal disorders, ...
Socio-economic consequences of longstanding illness
(2002-08-09)
This thesis focuses an old research area of social medicine, the social and economic consequences of chronic illness and factors modifying this effect. Historically, illness was the main predictor of poverty. Since then, ...
On Parkinson's disease and schizophrenia : case control studies, cellular localization and modelling of candidate genes
(2003-11-21)
to study the cellular expression patterns and mRNA levels of candidate genes in SZ, PD and control brains NURR1 is one good candidate gene for disorders with an involvement of the DA neuron system since knockout mice do not develop DA neurons...
HIV and SIV specific cellular immunity in macaque models
(2003-11-21)
Cellular immunity is believed to be an important prerequisite for an effective HIV vaccine. Accruing data from individuals able to contain HIV-1 replication during natural infection underscores the contribution of CD8+ T cells in viral control...
Health care financing in China : equity in transition
(2002-08-12)
The aim of the thesis is 1) to assess equity in the provision, financing and utilization of health services in the study counties, after the launching of the Chinese health reform, in relation to income and health status, 2) to assess equity...
Population health and inequalities in health : measurement of health-related quality of life and changes in QALYs over time in Sweden
(2003-03-07)
were available (Paper III).
Life expectancy for newborn males (females) increased by 3.68 (2.70) years from 1980/81 to 1996/97 (Paper IV). Expected QALYs increased by 2.64 (0.54). Older persons experienced considerable health gains over time whereas...
Facilitation of recovery after ischaemic stroke : early dexamphetamine and physiotherapy treatment
(2003-11-28)
, and residence of living were secondary outcomes. Patients were followed for twelve months. III) Pharmacokinetics of d-amph were analysed in 26 patients from study 1. IV) In the meta-analysis seven studies including a total of 172 patients with stroke (including...
Maternal deprivation and mood stabilizing drugs : effects on rat brain NPY
(2002-10-04)
of the hippocampus and the prevention of a kindling-induced downregulation of Y1-, and Y5-like receptors in the dentate gyrus and Y2-like receptors in the CA3 area of the hippocampus. In contrast, none of these parameters were affected by levetiracetam in normal rats...
Studies on sterol 27-hydroxylase (CYP27A1)
(2004-01-30)
Human sterol 27-hydroxylase (CYP27A1) has been studied in the present thesis with focus on substrate specificity and possible role of the enzyme for prevention of accumulation of cholesterol and cholestanol in tissues. Attempts have been made...