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Surgery and recurrence in Crohn’s disease
(2002-01-11)
risk for recurrent disease of 2.9 and 3.0 respectively was found. A
history of perianal disease implies a high probability of recurrent
disease. A decreased risk of recurrence was found in the age group 30-44
years at diagnosis....
Mortality and co-morbidity among patients with hemochromatosis and their first-degree relatives
(2010-05-14)
Genetic hemochromatosis (GH) is an autosomal recessive disease caused by
a C282Y mutation in the HFEgene, and is characterized by excess iron
accumulation in multiple organs. Classical manifestations of GH include
liver ...
Apoptosis and inflammation regulation after injury to the developing brain
(2015-09-25)
The brain shows greater plasticity in early life than in maturity, which paradoxically renders the organ more vulnerable to hypoxia-ischemia (HI)- and cranial irradiation (IR)- induced damage. Apoptosis after a HI insult ...
Delivery of DNA vaccines against cancer
(2006-10-06)
DNA vaccines against cancer have shown promising results in animal models. Efficient antigenspecific T cell responses and tumor protection have been demonstrated after vaccination with DNA encoding tumor antigens in mice. ...
Impaired response to HBV vaccination in HIV-1 infected children : immunopathological mechanisms
(2018-05-08)
HBV vaccination prevents HBV infection and related liver cancer. Immunological dysfunctions of Tfh and B cells in HIV-1 infected individuals may affect the response to HBV vaccine. The general objective of this thesis was ...