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Factors influencing the turnover of olfactory receptor neurons
(2000-12-29)
of tenascin-C, tenascin-X, tenascin-R and tenascin/J1 mRNAs were analyzed in the perinatal and adult rat spinal cord and olfactory system, as well as after lesions in the ventral funiculus of the spinal cord. Tenascin-C, -R and /J1 were differentially...
Vocational rehabilitation of unemployed sick-listed people in a Swedish rural area : an individual-level study based on social insurance data
(2000-11-28)
rural social insurance offices in Jämtland. Surprisingly, the study showed that the proportion of unemployed among the long-term sick-listed was lower in the rural area of Jämtland (15%) than in Stockholm (20%). However, as in Stockholm, the unemployed...
Pharmacological and hormonal effects on bone with emphasis on osteoporosis : experimental studies in the rat
(2001-02-23)
In this thesis influences of some hormones (17beta-estradiol and human
parathyroid hormone) and drugs (risedronate and verapamil) on bone were
investigated.
The effects of verapamil, a phenylalkylamine calcium ...
On vascular endothelial growth factor B and platelet-derived growth factor C : two members of the VEGF/PDGF family of growth factors
(2001-03-30)
Vascular endothelial growth factors (VEGFs), platelet-derived growth factors (PDGFs) and their receptors are important for normal development. They have also been implicated in many pathological conditions. VEGFs have been ...
Molecular endocrinology of target enzymes in androgen metabolism : implications for prostate cancer
(2001-03-02)
Genes that are responsible for variations in drug and hormonal responses
are sometimes also associated with the pathophysiology of diseases.
Understanding the aetiology of a disease is often essential for the
design of ...
Preeclampsia and other circulatory diseases during pregnancy : etiological aspects and impact on female offspring
(2001-03-01)
The aims of this thesis were to investigate and compare environmental effects on the liability of developing preeclampsia and gestational hypertension; to estimate the relative importance of genetic and environmental effects ...
Molecular diversity in the Notch receptor family
(2001-05-18)
We have studied the Notch family of transmembrane receptors, which play a crucial role in cell fate determination. The Notch signalling pathway represents a conserved mechanism to mediate signalling between adjacent, ...
Mapping of the specificity in MHC class I recognition by natural killer cells
(2000-11-24)
Natural killer (NK) cells represent the third major lymphocyte subpopulation. They are distinguishable from B and T lymphocytes by their surface phenotype, cytokine profile and the ability to mediate spontaneous cytotoxicity, ...
Regulation of virulence gene expression in Staphylococcus aureus
(2000-11-24)
The pathogenic bacterium Staphylococcus aureus has the ability to cause a wide variety of human diseases, ranging from superficial abscesses and wound infections to deep and systemic infections such as osteomyelitis, ...
Renal cell cancer : the role of physical activity and body size
(2001-02-02)
The aim of this thesis was to explore how physical activity, obesity, weight change, and birth weight influence the risk of renal cell cancer.
The relation between occupational physical activity and risk of renal ...