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Cryptic chromosome abnormalities in idiopathic mental retardation
(2001-12-21)
Mental retardation is a common disorder, affecting 1-3% of the population. In spite of improved diagnostic tools, the etiology can still not be established in half of the cases. Several lines of evidence indicate a genetic ...
Experimental design of phenotyping probe drugs with emphasis on CYP1A2 : their use in studies on genetic and environmental regulation of drug metabolism
(2003-05-02)
as a urinary collection was validated. Caffeine oral clearance (CL) in plasma correlated with that assessed in saliva (rs=0.97). The total oral caffeine CL correlated with the paraxanthine / caffeine concentration ratio in plasma (rs=0. 84), saliva (rs...
Pulmonary tuberculosis and HIV interaction in a setting with a high prevalence of HIV : clinical, diagnostic and epidemiological aspects
(2002-05-17)
and HIV endemic area.
Among 509 consecutive out-patients attending a university hospital in Ethiopia, 33.0% were culture-verified as having PTB. PTB patients, non-TB patients and controls were HIV-1 positive in 57.1%, 38.5% and 8.3% of cases...
Wound ventilation : a new concept for prevention of complications in cardiac surgery
(2003-09-05)
Cardiac surgery through an open chest wound is a major operation both in size and duration. The wound exposure to ambient air implies considerable risks. 1) Air may enter the heart and great vessels and embolize to the ...
Birth centre care : reproduction and infant health
(2004-04-02)
This thesis has two general aims, to investigate factors affecting
women s decision to have a second baby and to study the effect of birth
centre care on infant outcome. The specific aims were to investigate 1)
whether ...
Minimally invasive hernia surgery
(2003-04-25)
/inflammations, including intestinal obstruction, 58.99. The RR was 2.79 with TAPP and 0.57 with TEP compared to Lichtenstein operated patients....
Clinical application of QLF and DIAGNOdent : two new methods for quantification of dental caries
(2002-02-25)
General aim: The general objective of this thesis was to evaluate the clinical performance of two new methods for quantification of dental caries - the Quantitative Light-induced Fluorescence method (QLF) and KaVo ...
Linkage and association analysis in multiple sclerosis
(2001-09-03)
Multiple sclerosis (MS) is a chronic inflammatory disease of the central nervous system, which is characterized by relapsing or progressive demyelinating plaques in the brain and spinal cord. It is well established that ...
Vital exhaustion and coronary artery disease in women : biological correlates and behavioral intervention
(2003-05-01)
of CAD in women with ACS (OR=2.9, 95% Cl 1.3-6.2); elevated cortisol levels were found in patients with significant CAD (p<0.01); vital exhaustion a positive association was found between vital exhaustion and cortisol (p=0.05); and divided into quartiles...
Carbon dioxide de-airing in cardiac surgery
(2004-01-09)
.65% remaining air), while the 2.5mm and 6.35mm open-ended tube were much less efficient with >=82% and >19.5% remaining air, respectively, at 2.5-10 I/min C02 flows (p<0.001). When using the gas-diffuser, an open pleural cavity prolonged the time needed...