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Hepatitis C virus kinetics during antiviral treatment
(2004-03-05)
It is estimated that 170 million individuals have chronic hepatitis C virus (HCV) infection, whereof 20-30% will develop end stage liver disease within 20-30 years. Antiviral therapy can stop this deterioration and clear ...
Endocrine and metabolic aspects of adult Prader Willi syndrome with special emphasis on the effect of growth hormone treatment
(2003-09-05)
Prader Willi Syndrome (PWS) is a complex genetic disorder characterized by muscular hypotonia, hyperphagia, obesity and behavioural problems. Partial growth hormone (GH) deficiency and hypogonadism are common. Results of ...
HLA predisposition to human papillomavirus induced cervical neoplasia : population based studies from the Västerbotten county in northern Sweden
(2001-08-08)
Infection with human papillomaviruses (HPV) types 16 and 18 is the major
cause of cervical neoplasia. Although a high proportion of cervical
cancers (CXCA) harbor HPV genomes, only a small number of women infected
with ...
Linkage and association analysis in multiple sclerosis
(2001-09-03)
Multiple sclerosis (MS) is a chronic inflammatory disease of the central nervous system, which is characterized by relapsing or progressive demyelinating plaques in the brain and spinal cord. It is well established that ...
Autoimmune markers in autoimmune diabetes
(2003-12-19)
Type 1 diabetes mellitus (T1DM) is an autoimmune disease, characterized by autoimmune mediated loss of insulin secreting Beta-cells. The disease is associated with certain HLA class 11 haplotypes. HLA DR3-DQ2 and DR4-DQ8 are positively while DQ6...
An analysis of parents experiences and the caregivers role following the birth of a stillborn child
(2003-11-21)
The objective of this thesis was to describe and analyse parents experiences of hospital care and to describe caregivers role and attitudes to the management of stillbirth. To accomplish the overall aim, three studies ...
Arthroplasty in patients with femoral neck fractures
(2011-05-03)
The aim of this thesis was to analyze hip function and the health-related quality of life (HRQoL) in patients with a displaced fracture of the femoral neck treated with a cemented total hip arthroplasty (THA) or a ...
p16INK4A and p15INK4B in senescence, immortalization and cancer : gene transfer by adenovirus vectors
(2001-11-09)
The astrocytic gliomas are the most common form of brain tumors in
humans. The malignant progression from low grade (astrocytoma, grade II)
to high-grade (glioblastoma multiforme, grade, IV) astrocytomas is well
documented ...
Indoor environment and recurrent wheezing in young children
(2003-02-21)
/concrete slab foundation, compared with those living in buildings erected before 1940, OR 2.5 (1.3-4.8) and OR 2.5 (1.1-5.4). This was not primarily explained by differences in type of ventilation systems, measured ventilation rate, occurrence of house dust mite...
Observations on essential biochemical data profile in connection with restorative proctocolectomy in humans : vitamin B12 and fat absorption cited
(2001-10-18)
PATIENTS: The material includes 99 patients who consecutively received
handsawn pouch and ileoanal anastomosis, after mucosectomy. Sixty-five
patients were men and forty-four were women. The mean-age was 31.4 (range
17-59) ...