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Tumor gene therapy using Semliki forest virus replicons
(2001-11-26)
A major challenge in cancer research is to design effective vaccines that can break immunological tolerance to tumor antigens. Over the past ten years several immunotherapeutic strategies aimed at modulating the patient's ...
Trinucleotide repeats and neuropsychiatric phenotypes
(2001-11-02)
Genetic studies of affective disorders have yielded several chromosomal regions suggestive for linkage. Linkage analysis was performed in five families with unipolar affective disorder, collected from northern Sweden. Four ...
Minimally invasive hernia surgery
(2003-04-25)
Minimally invasive laparoscopic and open tension-free techniques have been evolved during the 1990's. Different laparoscopic techniques have been used, where the totally extraperitoneal hernioplasty (TEP) is a technically ...
Methods for measurement of vocal fold vibration and viscoelasticity
(2009-05-08)
The overall aim of the thesis was to develop new methods for analysis of vocal fold vibrations and viscoelasticity and to test them in human subjects.
In Study I the onset of vibration and irregular vocal fold ...
Lumbar muscle fatigue and recovery : evaluation of electromyography in patients with long-term low-back pain and in healthy subjects
(2002-11-22)
Background: Lumbar muscle function is considered to be an important component of longterm low- back pain. The change in the median frequency of the power spectrum of the electromyographic (EMG) signal is commonly used to ...
Birth centre care : reproduction and infant health
(2004-04-02)
This thesis has two general aims, to investigate factors affecting
women s decision to have a second baby and to study the effect of birth
centre care on infant outcome. The specific aims were to investigate 1)
whether ...
Linkage and association analysis in multiple sclerosis
(2001-09-03)
Multiple sclerosis (MS) is a chronic inflammatory disease of the central nervous system, which is characterized by relapsing or progressive demyelinating plaques in the brain and spinal cord. It is well established that ...
Observations on essential biochemical data profile in connection with restorative proctocolectomy in humans : vitamin B12 and fat absorption cited
(2001-10-18)
PATIENTS: The material includes 99 patients who consecutively received
handsawn pouch and ileoanal anastomosis, after mucosectomy. Sixty-five
patients were men and forty-four were women. The mean-age was 31.4 (range
17-59) ...
Temporomandibular joint involvement by systemic inflammatory disease with reference to pain modulation and joint tissue destruction
(2003-11-07)
Systemic inflammatory diseases may cause progressive destruction in the temporo-mandibular joint (TMJ). Involvement of this joint is associated with many clinical signs and symptoms of which pain is a major problem. This ...
Diabetic osteopathy : a study in the rat
(2012-03-09)
The present study on non-obese Goto-Kakizaki (GK) rats with type-2 diabetes and neuropathy was an attempt to describe and define pertinent features of diabetic osteopathy. Altogether, the study included 33 GK rats aged 12 ...