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Carcinogenic polycyclic aromatic hydrocarbons : role of human glutathione transferases in conjugate formation and DNA protection
(2001-09-28)
Polycyclic aromatic hydrocarbons (PAHs) are widespread mutagenic and
carcinogenic environmental pollutants, which requires metabolic
activation to electrophilic intermediates and subsequent covalent binding
to critical ...
Central-block techniques for reliet of labour pain
(2004-04-23)
I bolus dose and 20 minutes lockout, or CEI, 6 ml/hour. Extra dosing was permitted to the same possible maximum dose, 12 ml/hour. The PCEA group used 33 % less drug totally and 25% less drug per hour than the CEI group. Both groups had equally satisfactory...
Antidepressive and antipsychotic treatments : effects on nerve growth factor and brain-derived neurotrophic factor in rat brain
(2002-08-30)
Recently it has been reported that depression and schizophrenia, the two major psychiatric disorders, are characterized by loss of neurons in specific brain regions. Nerve growth factor (NGF) and brain-derived neurotrophic ...
Temporomandibular joint involvement by systemic inflammatory disease with reference to pain modulation and joint tissue destruction
(2003-11-07)
Systemic inflammatory diseases may cause progressive destruction in the temporo-mandibular joint (TMJ). Involvement of this joint is associated with many clinical signs and symptoms of which pain is a major problem. This ...
Particles in small airways : mechanisms for deposition and clearance and pharmacokinetic assessments of delivered dose to the lung
(2004-04-16)
BACKGROUND: Knowledge about lung deposition and clearance from airways of inhaled particles/drugs are essential for evaluation of health effects of inhaled
pollutants and to achieve optimal drug dose to the lung. The ...
HLA predisposition to human papillomavirus induced cervical neoplasia : population based studies from the Västerbotten county in northern Sweden
(2001-08-08)
Infection with human papillomaviruses (HPV) types 16 and 18 is the major
cause of cervical neoplasia. Although a high proportion of cervical
cancers (CXCA) harbor HPV genomes, only a small number of women infected
with ...
Lumbar muscle fatigue and recovery : evaluation of electromyography in patients with long-term low-back pain and in healthy subjects
(2002-11-22)
was somewhat higher for patients (ICC>0.6) than for healthy subjects. The initial median frequency and, to a greater extent, the slope were sensitive to the exerted torque. The patients differed from the healthy subjects by lower MVC torque, higher initial...
Bioactive peptides and proteins in disease
(2004-05-17)
Regulatory peptides and marker proteins are important to study in order to understand disease mechanisms. This applies of course also to our common diseases where all relationships are not yet known. Cancer and diabetes ...
Bile in the oesophagus contributes to the development and complications of gastro-oesophageal reflux disease
(2002-05-10)
cancer. Furthermore, patients with reflux symptoms twice weekly or more, for at least 6 months, and healthy volunteers were recruited and examined. Upper gastrointestinal endoscopy, circadian oesophageal acidity values, bilirubin levels, oesophageal...
A concept for treatment of sports related knee injuries
(2004-04-02)
The aim of the present thesis was, to evaluate local anaesthesia as ananaesthetic technique when performing knee arthroscopies, from a clinicaland economical point of view, and to describe the total costs for surgeryof ...