Search
Now showing items 1-10 of 37
Role of protein-tyrosine phospatases in insulin and glucagon secretion in pancreatic islets of healthy rats and spontaneously diabetic GK rats
(2004-03-26)
. At 3.3 mM glucose, 0.1-1 mM pV stimulated insulin secretion (p<0.05), while at 16.7 mM glucose 0.01-0.1 mM pV inhibited its secretion (p<0.05). These effects were not mediated by pV modulation of islet glucose metabolism, or by interference with Gi...
DARPP-32 in the striatum : multiple regulation and physiological role
(2001-08-24)
Protein phosphorylation is an important mechanism involved in
intracellular signal transduction. The activity of many proteins is
affected by their state of phosphorylation, which in turn is determined
by the combined ...
Constitutive and TCDD-induced expression of Ah receptor responsive genes with special focus on the brain and pituitary
(2002-12-27)
The 2,3,7,8-tetrachlorodibenzo-p-dioxin (2,3,7,8-TCDD) and related substances are ubiquitous environmental pollutants causing a number of pathological alterations, the most severe being progressive anorexia and body weight loss. The effects on body...
A concept for treatment of sports related knee injuries
(2004-04-02)
The aim of the present thesis was, to evaluate local anaesthesia as ananaesthetic technique when performing knee arthroscopies, from a clinicaland economical point of view, and to describe the total costs for surgeryof ...
Nano-electrospray mass spectrometry for the analysis of neurosteroids and related molecules
(2003-03-10)
of 1 pg/µL. Information about steroid structure was obtained from collision-induced dissociation (CID) spectra of 1 ng of steroid sulphate, while characterisation of the sulphate ester group required only 3 pg of material. Unconjugated oxosteroids were...
Diabetic osteopathy : a study in the rat
(2012-03-09)
The present study on non-obese Goto-Kakizaki (GK) rats with type-2 diabetes and neuropathy was an attempt to describe and define pertinent features of diabetic osteopathy. Altogether, the study included 33 GK rats aged 12 ...
Hepatitis C in chronic kidney disease and kidney transplantation : with special reference to epidemiology and treatment
(2003-10-31)
Hepatitis C (HCV) is a clinical problem in infected kidney transplant patients but is also a cause of renal disease and vasculitis. Standard therapy for HCV is a combination of interferon and ribavirin. Renal patients have ...
Ocular counter-rolling during head tilt
(2003-08-29)
static head tilt. The OCR increased with head tilt but the relative compensation to the amount of head tilt decreased. For example, a 15° head tilt induced 3° OCR which corresponds to a gain of 0.20. A 30° head tilt induced an even larger OCR (5°) which...
Appetitive and consummatory ingestive behavior : role of taste, dopamine and NPY
(2001-11-23)
The present thesis has examined the role of taste, dopamine and
neuropeptide Y (NPY) in the regulation of the two phases of ingestive
behavior: appetitive (approaching and handling of food) and consummatory
ingestive ...
Clinical application of QLF and DIAGNOdent : two new methods for quantification of dental caries
(2002-02-25)
of carious lesions on smooth surfaces and good intra- and inter-operator agreement for lesions on occlusal surfaces. 3) With respect to clinical cut-off thresholds for dentinal caries on occlusal surfaces, no definite recommendations for DIAGNOdent could...