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Growth factors and vasoactive substances in intrauterine growth restriction and preeclampsia
(2001-11-22)
Fetal growth restriction (FGR) is, next to prematurity, the second leading cause of perinatal morbidity and mortality. To reduce perinatal morbidity and mortality it is important to identify such fetuses in utero in order ...
New approaches for diagnostics and therapy of allergy to pets
(2015-04-01)
Allergic diseases have been described already in 900 AD but today allergic diseases have reached epidemic proportions. About 30% of the world population is affected. Typical allergic symptoms of the immune system’s reaction ...
Molecular regulation and analysis of neural stem and cancer cell characteristics
(2012-05-25)
and VPA treatment respectively. In addition, we show that RNA knockdown of the DNA glycosylase OGG1 in C6SCs affects differentiation potential and increases the histone modification mark, acetylation of histone 3 in lysine 56 (H3K56ac) associated...
Interactions between innate immune effectors and multidrug resistant bacteria
(2020-10-14)
Antibiotic resistance is an increasingly difficult problem in the clinic, where conventional antibiotics are failing, and new alternative solutions are in high demand. Infections caused by Gram-negative bacteria with multi ...
Integrated assessment of environmental and human health risks of antibiotic residues and resistance for environmental and health policy
(2021-04-27)
Background: Antibiotic resistance is a global health crisis and a serious threat to progress in achieving the Sustainable Development Goals. This requires a One Health response that recognises the link between human and ...
Autophagy and VPS34 as targets in anti-cancer therapy
(2021-08-20)
Autophagy (Greek for self-eating) is a cellular pathway that breaks down cytoplasmic components to fuel metabolism. In this way, autophagy maintains cellular homeostasis and sustains survival during stress conditions. In ...
Every bug counts : neonatal colonization and infection of Gram-negative bacilli : aspects on antibiotic resistance in Sweden and Ecuador
(2020-09-18)
(adjusted OR, 95% CI: 1.6-9.4) to die before discharge compared to the uninfected matched control group. Overall, 6.5% (7/107) of the isolates were multidrug-resistant. The incidence of both GNB-EOS and GNB-LOS was lower than reported in previous studies...
Apoptotic cell death in neural stem cells exposed to toxic stimuli
(2007-09-14)
Neural stem cells (NSCs) play an important role in the developing nervous system and in the adult brain, where mitotic regions such as the subventricular zone (SVZ) remain active. In spite of the intense ongoing research ...
Hantaviruses, escapees from the death row : viral mechanisms towards apoptosis resistance
(2019-10-25)
Over the past decades, humanity has witnessed a constant stream of emerging pathogenic RNA viruses. The recurrent outbreaks of Ebola virus in Africa, the emergence of West Nile virus in North America and the sporadic but ...