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Studies of receptors and modulatory mechanisms in functional responses to cysteinyl-leukotrienes in smooth muscle
(2001-05-18)
inhibited the contractions induced by LTD4, and abolished the LTE4-induced contractions. The contractions induced by LTC4 in the guinea-pig trachea and ileum were resistant to CysLT, receptor antagonism and competitively inhibited by the dual CysLT1/CysLT2...
Biosynthesis of leukotriene B4 in hematological malignancies
(2005-05-27)
Leukotrienes (LT) are biologically active metabolites of the fatty acid
arachidonic acid (AA). After liberation of AA by phospholipase A 2 (PLA
2), this fatty acid can be converted to leukotrienes, lipoxins,
prostaglandins ...
Hormones, muscles and oncological outcome in men with rectal cancer
(2019-10-04)
in muscle areas of the lower trunk and pelvis. The estimated change (95% CI) of muscle area increase per 100 mg of T enanthate dosage increase was 0.622 cm2 (0.394, 0.850) for psoas; 1.789 cm2 (1.317, 2.261) for paraspinal muscles; 2.530 cm2 (1.627, 3...
Ontogeny of perception of maternal and nosocomial stimuli in infants
(2018-02-27)
Preterm born infants in neonatal units experience unusual sensory inputs that can shape and nurture their developing brains differently from full-term healthy newborn infants. To improve the care of preterm infants and ...
The role of SOXC transcription factors in B-cell development and lymphoid malignancies
(2017-09-15)
is characterized by the t(11;14)(q13;q32) CCND1/IGH translocation that results in high expression of cyclin D1. This translocation takes place at the pre-B cell stage and is generally recognized as the hallmark and primary oncogenic event in the evolution of MCL...
An object's smell in the multisensory brain : how our senses interact during olfactory object processing
(2021-05-28)
Object perception is a remarkable and fundamental cognitive ability that allows us to interpret and interact with the world we are living in. In our everyday life, we constantly perceive objects–mostly without being aware ...