Search
Now showing items 1-10 of 10
Response of human skeletal muscle to chronic and acute exercise and ischemia : muscle dimensions, tissue water and blood flow as measured by magnetic resonance imaging and comparative methods
(2001-05-18)
The aim of this study was to investigate the response of human skeletal
muscle to exercise, training and ischemi and to evaluate if magnetic
resonance imaging (MRI) could be used to measure regional muscle
cross-sectional ...
Escaping the riptide : probing the malleability of cognition
(2022-05-25)
Cognitive abilities are essential for functioning in daily life – even something as mundane as going to the grocery store taps into a variety of cognitive functions. Exactly how and under what circumstances they can be ...
Probing and pushing potential genetics, development and training of cognitive functions
(2012-05-15)
Capacities of cognitive functions increase considerably during childhood and adolescence. This development is of importance as poor development can predict lower performance on academic skills. Furthermore, severe impairment ...
Paediatric intensive care in Sweden : i mechanical ventilation and central haemodynamics : ii outcome of paediatric intensive care with special reference to respiratory failure
(2008-05-23)
The ABC of acute care is to maintain Airway, Breathing and Circulation or
oxygen delivery, which depends on the product of cardiac output (CO) and
oxygenation. Thus knowledge of how different modes of mechanical
ventilation ...
Working memory : development, disorders and training
(2004-04-23)
Working memory (WM) is the ability to keep information online during a short period of time. Brain regions underlying WM functioning are found in the frontal and parietal cortices. It is largely unknown to what extent the ...
Genes of the serotonergic system and susceptibility to psychiatric disorders : a gene-based haplotype approach
(2006-05-24)
Psychiatric disorders are complex, non-mendelian disorders. Complex disorders are ultimately determined by a number of genetic and environmental factors, and the effect of each factor may be obscured or confounded by others. ...
Phospholamban antisense oligonucleotides improve cardiac function in murine cardiomyopathy
(Nature Publishing group, 2022-08-18)
Heart failure (HF) is a major cause of morbidity and mortality worldwide, highlighting an urgent need for novel treatment options, despite recent improvements. Aberrant Ca2+ handling is a key feature of HF pathophysiology. ...
Mechanistic studies of a novel inhibitor of the ubiquitin-proteasome system
(2019-05-03)
The ubiquitin-proteasome system (UPS) not only maintains cellular proteostasis, but plays an essential role in multiple vital cellular processes, including survival and growth. Proteasomal inhibitors, such as bortezomib, ...
Exploring immunotherapeutic targets in the tumor microenvironment
(2015-11-19)
The immune system has developed along with the evolution of increasingly complex
cellular organisms to sustain homeostasis and protect from threats. Cancer, a detrimental
side effect of increasing organismic complexity, ...
Dynamics of proteinopathies in Alzheimer’s disease as measured by PET and CSF biomarkers
(2018-10-05)
Alzheimer’s disease (AD) is a neurodegenerative disorder characterized by the extracellular aggregation of the amyloid-β (Aβ; amyloid) peptide and the intraneuronal accumulation of the protein tau. Independently, and in ...