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Importance of insulin-like growth factor-1 receptor and EWS/FLI-1 fusion protein in growth and survival of two different types of neuroectodermal tumor cells
(1998-11-20)
Treatment with comparatively low doses of the 3-hydroxy-3-metylglutaryl coenzyme A (HMG-CoA) reductase inhibitor lovastatin caused growth arrest in both melanoma cells and Ewing's sarcoma (ES) cells. In melanoma cells ...
Carbohydrate-mediated adhesion in Plasmodium falciparum malaria
(2000-02-02)
Characterization of virulence factors in P. falciparum malaria is essential in order to identify new therapeutic and prophylactic targets. Rosette formation, the binding of uninfected red blood cells to parasite-infected ...
Human newborn behavior during exposure to maternal and other odors
(2001-08-23)
Olfaction appears to play a pivotal role in immediate postnatal interactions between mammalian mothers and their offspring. The present study examined: (1) whether and how the newborn human infant and its mother communicate by means of olfaction; (2...
Oncologic and functional outcomes after robot-assisted radical hysterectomy for cervical cancer
(2020-10-16)
.06-4.26). The postoperative complication rates (37%) and costs were similar, but the hospital stay was shorter than following ORH. The nationwide study (Study II) showed no statistical difference between RRH and ORH with respect to 5-year OS (HR 1.00; 95% CI, 0.50-2...
Human muscle response to sprint exercise and nutrient supply with focus on factors related to protein metabolism
(2016-12-21)
The overall aim of the present thesis was to study the muscular response to repeated bouts of
30-s sprint exercise. This type of exercise gives rise to a profound metabolic perturbation that
might counteract an ...
Cost analysis and policy implications in psychiatric care
(2009-04-01)
in Sweden in 2001 (Study I) was estimated at MSEK 85 774 (M€ 9 426, €1= SEK9.1). Indirect costs were totally predominant and constituted about 80% of the total cost, i.e. production losses due to early retirement, sickness absence and premature death...
Re-establishing reading skills of elderly low vision patients : studies on Swedish low vision clinic clients
(2013-02-13)
This thesis is based on the project "Reading skills, reading training and technology for the visually handicapped - Prospects for the 1990s," carried out at the Department of Educational Research of the Stockholm Institute ...
Inflammatory proteins in the CNS-relation to Alzheimer's disease
(2005-05-18)
Most neurodegenerative disorders are characterised by an inflammatory process in the brain. Alzheimer's disease (AD) is a progressive neurodegenerative disorder and the most common form of dementia in the elderly. Activated ...
Learning not to fear : extinction, erasure, and the recovery of fear memories
(2013-01-18)
Much of the progress in understanding the mechanisms underlying the formation and persistence of fear memories comes from studies of Pavlovian conditioning and extinction. Recently, considerable interest has been turn to ...
Employing epigenetic marks to detect cancer : studies on nasopharyngeal carcinoma and lung cancer
(2015-02-02)
) was confirmed to be hypermethylated in NPC by bisulfite cloned sequencing, bisulfite pyrosequencing and methylation specific PCR. ITGA9 was downregulated in NPC clinical samples and 5-aza-2′-deoxycytidine restored the expression of ITGA9 in NPC derived cell...