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Regulation of cytochrome P4502C7 : effects of growth hormone and vitamin A
(1996-03-29)
Members of the CYP2C subfamily, highly represented in rat liver, are constitutively expressed genes that encode enzymes that metabolize endogenous substrates such as steroids. Expression of P4502C11 and P4502C12 in rat ...
Adolescent sexuality and sexual abuse : a Swedish perspective
(2001-05-02)
In the late 1980’s, teenage abortions and genital chlamydial infections were increasing adolescent health problems in Sweden, indicating unsafe sex practices among young people. The emergence of HIV highlighted the need ...
Intravenous induction of anaesthesia in children : aspects on propofol and etomidate
(2016-04-29)
Propofol is today the most commonly used drug for induction of anaesthesia and for short-term sedation. However, one specific problem is that intravenous injection of propofol often results in quite severe injection pain, ...
Getting in and out of shape : relevance for organ formation and cancer
(2014-09-11)
that sequester Crb3 and Par3 polarity complexes inside the cell. In human tumors from breast and colon cancer patient’s p60 AmotL2 expression correlates with loss of tissue architecture and cell polarity. Furthermore we provide data showing that p60 AmotL2 acts...
Endothelial dysfunction in atherosclerosis and type 2 diabetes : clinical and molecular studies of the role of endothelin and arginase
(2018-05-08)
Background: Atherosclerosis is a modern world scourge and the number of people worldwide diagnosed with type 2 diabetes (T2D) is on the rise, causing much morbidity and mortality. Endothelial dysfunction (ED) is an early ...
Vocational rehabilitation of unemployed sick-listed people in a Swedish rural area : an individual-level study based on social insurance data
(2000-11-28)
The long trend of low unemployment and increasing economic growth in Sweden was broken in the early 1990 s. In a short time, the rate of unemployment had risen from 1.3% in 1990 to 8.2% in 1993. A previous study made in Stockholm showed that among...
Avidity-guided radionuclide therapy for thyroid cancer
(2022-09-01)
The treatment of differentiated thyroid cancer has three main modalities: surgery, hormone suppression and radioiodine therapy. Effective radioiodine therapy requires cancer cells to be iodine avid, i.e. exhibit relatively ...
Pathophysiology in postterm pregnancy : epidemiology, risk factors and cervical ripening
(2012-05-07)
between 1992 to 2006 (total n=1,176,131), was identified. In paper II, a cohort of singleton births from 1995 to 2008 (n=1,191,336) was identified in the Swedish Medical Birth Registry, out of which 3,787 were born to a mother with a previous diagnosis...
Improving leadership through the power of words and music
(2014-09-18)
Background: Poor leadership is highly prevalent and associated with destructive processes in the workplace, including stress related ill health. Yet, the applied methods to improve leadership practices are rarely grounded ...
Psychological distress and breast cancer : a bidirectional link
(2022-11-09)
Psychological distress is one of the six vital signs among patients with cancer. An increased risk of psychiatric disorders has also been reported among cancer patients, compared with the general population. On the other ...