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Care by districts nurses : management of patients with chronic-pain conditions, patient satisfaction and effects of pain advisers
(2001-05-10)
This thesis focuses on some aspects of primary health care in Sweden before and after the introduction of "pain advisers": the district nurses opinions regarding their knowledge, management and documentation of patients ...
Defining the role of migratory dendritic cells in priming T cells to mycobacteria
(2022-05-16)
Dendritic cells (DCs) are professional antigen-presenting cells that bridge innate and adaptive immunity by priming T cells. DCs residing at body surfaces such as skin sense invading microbes and respond by internalizing ...
The quality of the physical environment and its association with activities and well-being among older people in residential care facilities
(2016-11-21)
The physical environment can influence older people’s health and well-being, and is often mentioned as being an important factor for person-centred care. Due to high levels of frail health, many older people spend a majority ...
Heart rate variability in patients with stable angina pectoris
(2009-01-16)
The rate and modulation of the heart beat (i.e. heart rate variability; HRV) are controlled by the autonomic nervous system. Cardiac sympathetic activation decreases and parasympathetic increases HRV. Measurements of HRV ...
Improving animal models to understand gene regulation in human diseases
(2021-10-29)
The role of animal models in understanding biological processes and their dysregulations in humans is imperative and established in the research community. While extensive resources and knowledge on the genetic information ...
Insulin signalling and TBC1D1 in skeletal muscle metabolism
(2011-11-18)
Type 2 diabetes mellitus (T2DM) has taken the form of a pandemic disease globally as people adopt a more western lifestyle. High circulating glucose levels indicates that an individual is in the risk zone for developing ...
Stress, depression, and other psychiatric disorders : an epidemiological approach to studying the causes and consequences for in vitro fertilization outcome and polycystic ovary syndrome
(2017-04-20)
Reproductive epidemiology, psychiatric epidemiology, and pharmacoepidemiology come together in this thesis which is comprised of four studies and divided into two parts.
Part 1 examines the impact of stress and ...
Robot-assisted laparoscopy and sentinel node biopsy in high risk endometrial cancer
(2018-11-15)
Surgery is standard treatment for early stage endometrial cancer (EC), the most common gynaecological malignancy in developed countries. Traditionally, surgery has been performed by laparotomy (LT). Comprehensive surgical ...
Pharmacological and analytical studies of the cyclin dependent kinase inhibitors
(2009-10-30)
, glomerulonephritis and inflammatory diseases. (R)-roscovitine (Rosco) is a synthetic tri-substituted purine that inhibits selectively Cdk1, 2, 5, 7 and 9. Rosco has shown promising cytotoxicity in cell lines and tumor xenografts. Rosco so far has only demonstrated...
Effect of cycline-dependent kinase and matrix metalloproteinase inhibitors on hematopoietic and leukemic cells
(2008-10-24)
and brain fitted a two-compartmentmodel in both adult and pups. Pharmacokinetics was age-dependent with a terminal elimination half-life of 7h in brain and plasma in pups compared to <0.5 h in adult rats. Brain exposure to roscovitine expressed as AUC brain...