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Family-based dementia care : experiences from the perspective of spouses and adult children
(2001-05-16)
Spouses' and adult childrens' experiences of being a caregiver to a
relative with dementia were investigated and an intervention study was
carried out and evaluated.
Study I aimed to investigate how adult children ...
Assessment of DNA damage, oxidative stress and inflammation in chronic kidney disease patients : and a clinical study of a dietary supplement
(2012-01-09)
Decreased kidney function is associated with higher levels of oxidative stress, inflammation and malnutrition. Chronic kidney disease (CKD) patients have a higher risk to develop cardiovascular disease, atherosclerosis and ...
On CNS injury and olfactory ensheathing cell engraftment strategies
(2005-11-18)
The intrinsic regenerative capacity of the adult mammalian central nervous system (CNS) is limited because of lack of nerve-growth stimulatory factors and presence of an insurmountable molecular environment for injured ...
Exploration of large molecular datasets using global gene networks : computational methods and tools
(2019-08-02)
Defining gene expression profiles and mapping complex interactions between molecular regulators and proteins is a key for understanding biological processes and the functional properties of cells, which is therefore, the ...
L-DOPA-induced signaling pathways and neuroepigenetic mechanisms in experimental parkinsonism and dyskinesia
(2014-11-07)
In patients with Parkinson’s disease (PD), the restoration of depleted striatal dopamine by chronic administration of its precursor, L-DOPA, results in the emergence of debilitating involuntary movements. This complication, ...
Dynamics of proteinopathies in Alzheimer’s disease as measured by PET and CSF biomarkers
(2018-10-05)
Alzheimer’s disease (AD) is a neurodegenerative disorder characterized by the extracellular aggregation of the amyloid-β (Aβ; amyloid) peptide and the intraneuronal accumulation of the protein tau. Independently, and in ...
Experimental spinal cord injury : methodological and neuroimmunological contributions with some historical background
(2011-01-19)
type controls, behavioral recovery and axonal regeneration were evaluated after spinal cord overhemisection. In another set of KO mice (STAT4, STAT6, IFNγ, IFNγR and IRF1) and their corresponding wild type controls inflammatory and glial cell reactions...