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Diabetes mellitus, socioeconomy and self-rated health : population-based studies in cohorts registered in the diabetes incidence study in Sweden
(2001-02-26)
The studies presented in this thesis analyzed the impact of diabetes
mellitus on socioeconomy and selfrated health, focusing on how the
consequences of diabetes develop during the first decade after the
diagnosis.
The ...
The assessment and treatment of long-term, non-specific spinal pain : behavioural medicine, a cognitive-behavioural perspective
(2000-11-24)
Background: Matching treatment specifically to the needs of long-term, non-specific spinal pain (LTSP) patients might greatly enhance treatment efficacy, but the heterogeneity of patients has hindered this development. ...
Proteasome targeted therapy in arthritis models : effects on pain and inflammation
(2010-09-24)
The ubiquitin proteasome system (UPS) regulates numerous cellular
functions by selectively degrading cellular proteins. It controls
activation of the transcription factor NF-ĸB which is involved in the
expression of ...
Tissue biomarkers in prostate cancer
(2009-09-25)
Prostate cancer (PC) is the most common male cancer in the western world. Better biomarkers are needed to support diagnosis, prediction of prognosis and treatment decision Radical prostatectomy (RP) specimens are routinely ...
Depression in youth and adults : etiology, outcomes, and comorbidities
(2022-02-02)
Depression is a common and debilitating mental disorder characterized by low mood, loss of interest in activities, and long-lasting functional impairment. It is a worldwide psychiatric illness with a wide range of ages of ...
Cancer after solid organ transplantation : incidence, risk factors, and survival
(2022-11-25)
Background: Solid organ transplant recipients (OTRs) are at increased risk of cancer compared with the general population, mainly due to post-transplant immunosuppressive treatment. Furthermore, once diagnosed with cancer, ...
Healthcare financing challenges and opportunities to achieving universal health coverage in the low- and middle-income country context
(2020-02-05)
uninsured to use MTP for healthcare. Applying the two-part regression model in study IV, we found that in comparison with the uninsured, the average OOP payment was 6.4% (p<0.001) smaller among the insured for such healthcare utilization. Nonetheless...
Factors affecting growth, differentiation and apoptosis of osteoblastic and osteosarcoma cells
(2008-10-17)
Osteoblasts play a fundamental role in determining bone structure and function. These cells originate from mesenchymal stem cells (MSCs) and through proliferation and differentiation develop into preosteoblasts and then ...
Interplay between mitochondria, primary cilium, diabetes and its complications
(2016-12-12)
Diabetes is one of the major health problems of the 21st century. Dysfunction of the insulin secreting pancreatic β-cell together with insulin resistance is central to the pathogenesis of type 2 diabetes mellitus (T2DM). ...