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Ambulation in persons with myelomeningocele
(2001-02-22)
The aim was to study ambulatory function in persons with
myelomeningocele. Different systems used to classify the extent of motor
paresis were compared. The classification according to five commonly used
systems showed a ...
Genetic studies in familial non-BRCA breast cancer
(2017-11-09)
an overrepresentation of endometrial cancer in the non-BRCA families with a 6.36 % proportion (CI 4.67–8.2) compared to the proportion in the general population in the reference years 1970 (3.07 %) and 2010 (2.64 %). The main finding of the study was the strong support...
Studies of stem cell and adhesion proteins in breast cancer
(2014-10-06)
Breast cancer is the commonest cancer and second leading cause of cancer death in women. It has been shown that breast cancer tumorigenic/stem cell like cells are CD24-/low CD44+EpCAM+. These cells constitute less than 5% ...
Injuries, risk factors, consequences and injury perceptions in adolescent elite athletes
(2017-09-28)
Background: Injury and health data are not fully explored in adolescent elite athletes, yet essential for understanding injury risk, consequences of injuries and developing injury preventive programs.
Aims: To explore ...
The destiny of natural killer cells in the tumor microenvironment : to be suppressed or activated?
(2014-03-07)
In the mid-70s, the term “natural” was used based on the functional properties of NK cells where they recognize and lyse certain tumor cells without requirement of prior immunization. Although NK cells are “natural” in ...
Expression of inflammatory and insulin signaling genes in acute and chronic stress
(2010-05-17)
The acute surgical stress response induces a short-term inflammatory and insulin resistant condition, commonly producing hyperglycemia, which is strongly associated to morbidity and mortality in postsurgical patients. The ...
Lymphangiogenesis and lymphatic metastasis
(2005-11-18)
The major cause of cancer mortality is metastasis, which relies on the growth of blood vessels (haemangiogenesis) and lymphatic vessels (lymphangiogenesis). Whereas the field of haemangiogenesis has been relatively thoroughly ...
Advancing cancer immunotherapy by exploring NK cell education, antibody targeting and tissue homing : stay tuned for directions reaching beyond the natural biology
(2022-10-21)
Cancer immunotherapy is a fast-growing field. The natural killer (NK) cells’ innate ability to detect malignant cells and capacity to perform antibody-dependent cellular cytotoxicity (ADCC) together with low risk of inducing ...