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Dietary prevention of gastrointestinal cancer : epidemiologic studies of fruit, vegetables and cereals
(2000-12-22)
The widely accepted inverse associations between fruit, vegetables,
dietary fiber and colorectal cancer risk, have recently been called into
question. In addition, dietary studies of certain cancers, such as
adenocarcinomas ...
New evidence on germ-cell testicular cancer aetiology
(2004-01-09)
evaluated recent trends in testicular cancer incidence in Northern European countries.
Using data from birth records and from the Swedish Cancer Register, we carried out a casecontrol study of 628 cases and 2,309 controls. We aimed at investigating...
Semliki forest virus-derived packaging system for production of retroviral vectors
(1998-11-20)
Gene therapy is a treatment of disease by transfer of genetic material into somatic cells of an individual. Successful gene therapy depends on a delivery system which can efficiently transfer the gene into target cells and ...
Functional and bioinformatical studies of the TGFb superfamily : identification and characterization of ALK7
(2001-11-02)
The transforming growth factor beta (TGFbeta) superfamily of polypeptide
growth factors encompasses more than 30 diverse mammalian members. They
are involved in most cellular processes, ranging from cell proliferation
and ...
Oxygen sensing in myeloid cells : implications for physiology and cancer
(2020-07-31)
All mammals depend on oxygen in order to produce life-essential energy. They acquire oxygen (O₂) through inspiration. In the lungs, O₂ is gathered by erythrocytes that consequently deliver it to all cells by the cardiovascular ...
Cellular mechanisms of human muscle fatigue and disease-related loss of muscle function
(2020-08-27)
A loss of skeletal muscle function and mass is a hallmark of several diseases resulting in a dismal life quality and poor prognosis. Impaired intracellular Ca2+-handling has been proposed as an underlying cause of these ...
Investigation of T cell driven arthritis induced by mannan in ZAP70 mutated SKG mice
(2016-08-10)
over more than 10 generations on B10.Q and B6.Q genetic backgrounds. Arthritis susceptibility is unaffected by the genetic backgrounds investigated, allowing the use of the SKG model on these common strains. This finding opens many possibilities...
Impact of Mycobacterium tuberculosis and HIV-1 on innate immune mechanisms
(2012-11-22)
Human immunodeficiency virus type 1 (HIV-1), a causative agent of acquired immunodeficiency syndrome (AIDS), and Mycobacterium tuberculosis (Mtb), a causative agent of tuberculosis (TB), are among the leading causes of ...
Carbon-graphite fiber-reinforced polymers for implant suprastructures
(2009-04-03)
Carbon-graphite fiber-reinforced polymers (CGFR) can be used as the core material for implant-retained prostheses as an alternative to metal frameworks. The purpose was to formulate and develop carbon-graphite fiber-reinforced ...
Oesophageal cancer : on surgery and aetiology
(2010-05-14)
Oesophageal cancer is a common type of cancer with a dire prognosis. It
is globally the eight most frequent malignancy and the sixth leading
cause of death from cancer. The doctoral research described in this
thesis has ...