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Corneal cellular proliferation and wound healing
(2000-10-27)
Background: Cellular proliferation plays an important role in both physiological and pathological processes. Epithelial hyperplasia in the epithelium, excessive scar formation in retrocorneal membrane formation and ...
Regional pulmonary vasoreactivity, with special reference to nitric oxide, prostacyclin and body posture
(2009-10-02)
The primary aim of the study was to investigate possible mechanisms behind the improved arterial oxygenation in ventilator-treated patients with acute lung injury (ALI) or acute respiratory distress syndrome (ARDS) when ...
Studies of changes in volume in right ventricle with electrical bio impedance
(2002-12-12)
In intracardiac impedance, electrical bio-impedance is measured inside the heart. This signal is known to reflect the volume of blood passing in and out of the ventricles. In transthoracic impedance the measurement current ...
Adolescent sexuality and sexual abuse : a Swedish perspective
(2001-05-02)
In the late 1980’s, teenage abortions and genital chlamydial infections were increasing adolescent health problems in Sweden, indicating unsafe sex practices among young people. The emergence of HIV highlighted the need ...
Amino acid predictors of HIV-1 coreceptor use in different subtypes and their application to antiretroviral treatment
(2014-01-10)
, their disease progression patterns, as well as in their coreceptor use phenotype distributions. The coreceptor use phenotypes of HIV-1 are based on which coreceptor the virus uses for cell entry, with the two main coreceptors being CCR5 and CXCR4, corresponding...
The male predominance in oesophageal adenocarcinoma and the role of sex hormones
(2023-02-28)
Oesophageal adenocarcinoma is a subtype of oesophageal cancer with rapidly rising incidence over the last decades. This rise in incidence is strongest in western countries and more among men than in women, with a male predominance of up to 9:1...
Rheumatoid arthritis : pharmacological modulation of cytokines : aspects of clinical response and endocrine regulation
(2006-01-06)
Rheumatoid arthritis (RA) is a systemic inflammatory disease primarily affecting the joints. In the pathogenesis several cells of the immune systeme and messengers of the immune systeme, cytokines, are important. In this ...
Endogenous thrombospondin-1 and proteases in the regulation of lymphocyte adhesion and motility
(2008-09-26)
lipoprotein receptor-related protein (LRP)/CD91. Interaction of TSP-1 with its cell surface receptors calreticulin (CRT), LRP and integrin associated protein (IAP)/CD47 was promoting motility of T cells in 3D collagen through CD47. T cell surface TSP-1 also...
Understanding inflammation requires neuroscience
(2022-03-01)
Inflammation and its resolution are processes subject to neural regulation (1). The best-characterized immune-regulating reflex is the “inflammatory reflex”, in which the efferent branch of the vagus nerve plays a central ...
Untangling the contribution of untranslated regions to mRNA translation in health and disease
(2022-01-19)
such as the mTOR pathway and the integrated stress response. In paper II, we applied nano-cap analysis of gene expression (nanoCAGE) and identified 5’UTR variants containing upstream open reading frames. In combination with the development of a reporter...