Search
Now showing items 1-10 of 117
T-cell mediated control of Epstein-Barr virus infection : viral mechanisms of immune escape
(1998-12-31)
Mechanisms regulating the immunogenicity of Epstein-Barr Virus (EBV)-encoded CTL peptide epitopes and their contribution to the escape of virus infected cells from CTL-mediated immunosurveillance were the subject of these ...
Immunopathology and signalling molecules involved during experimental African trypanosomiasis
(2000-09-21)
In humans, African trypanosomiasis occurs in two forms; the chronic West African form is caused by T.b. gambiense and the acute or subacute East African form is caused by T.b. rhodiense. Trypanosomes are transmitted by ...
Pathogenesis of the recently identified human herpesviruses 6 and 8
(2000-10-13)
associated with new lymphotropic
herpesviruses, i.e. human herpesviruses (HHV) 6 and 8.
HHV-6 is a ubiquitous virus and a relation to MS has been suggested since
the virus has been detected in MS plaques in the brain. The relation
between HHV-6 and MS...
Suppressive DNA vaccination in experimental autoimmune encephalomyelitis
(1999-11-26)
)-EAE. Vaccination with DNA encoding MOG91-108 suppressed clinical signs of EAE, after MOG91-108-challenge.
In conclusion, vaccination with DNA encoding autoantigenic peptides suppresses EAE. Presence of ISS and a local type 1 cytokine milieu is decisive...
Leishmania and HIV-1 interaction : immunopathogenic mechanisms
(1999-12-27)
relapse following successful initial response. Heat-inactivated (HI)-HIV-1 inhibited Leishmania-induced cell proliferation, but not IL-6 and TNF-[alpha] secretion, suggesting that the parasite can activate HIV. In addition, both HI and live HIV led...
Mechanisms of immune escape in EBV associated malignancies : Hodgkin's disease and Burkitt's lymphoma
(1999-09-10)
within tumor, infiltrating lymphocytes (TILs), cytokine mRNA expression, cell phenotype and EBV specific Cytotoxic activity were analysed in biopsies from 8 EBV carrying and 6 EBV negative HD lesions. Neither the pattern of lymphokine production, nor...
Biochemical and epidemiological characterization of serogroup C rotavirus
(2000-05-03)
into the endoplasmic reticulum and a final maturation into double capsid particles. We demonstrated that vp6 alone has the capacity to organize into viroplasmic structures, while additional viral proteins were required for the formation of single capsid particles...
Type-specific human papillomavirus antibodies : detection, characterization and application in seroepidemiology
(1999-11-05)
among pregnant women in Stockholm, Sweden, was found to have increased 1.5-fold from 1969 to 1983, but has remained stable during the 1980s. Antagonism between the benign HPV type 6 infection and the oncogenic HPV type 16 infection in cervical...
On the control of the microflora in the gastro intestinal tract : functional examples of antibacterial peptides from Helicobacter pylori and mouse small intestine
(2000-09-08)
The human microflora contains at least 400 different species mainly localized to the gastro-intestinal tract. This indigenous flora is controlled by host factors as well as by the interference within the microbial community ...
Taeniasis and cysticercosis in Honduras : epidemiological, serological, and clinical aspects
(1999-01-15)
conducted in Tegucigalpa, Honduras, demonstrated that 16% of 404 individuals investigated were seropositive. Two (0.6%) cases of taeniasis were identified, both in individuals who had recently migrated from rural areas. In a clinical study in Tegucigalpa...