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Studies of androgen receptor gene mutations in patients phenotypically ranging from complete androgen insensitivity to men with preserved fertility
(2000-09-08)
The androgen insensitivity syndrome (AIS) is the single most common cause
of male pseudohermaphroditism, i. e., deficient masculinization which is
not explained by disturbed testis development. In its most severe form ...
Epidemiological studies on type 2 diabetes : assessment of diabetes risk factors and study participation
(2012-02-02)
Type 2 diabetes is a disease with increasing prevalence. Better knowledge of risk factors may form the bases for specific interventions and preventive measures. The aim of this thesis was to contribute to the knowledge on ...
Gastroesophageal reflux : etiological factors
(2007-05-18)
Gastroesophageal reflux disease (GERD) is one of the most common health
problems in the Western world today, affecting up to 20% of the adult
population weekly and 50% monthly, generating substantial suffering among
patients ...
Determinants of hearing impairment in Swedish hunters : an e-epidemiological approach
(2016-04-08)
Background: 290 236 persons bought a hunting license in Sweden 2014/15. Hunters are
spread all over the country and come from all socioeconomic groups. Recreational fiearms
can produce peak noise levels between 156-164 ...
Leisure in late life : patterns of participation and relationship with health
(2008-05-20)
The overall aim of this thesis was to investigate aspects of leisure
participation in late life. More specifically, differences in
participation rates between two cohorts of older adults and changes in
leisure activities ...
Pharmacoepidemiologic studies of drug safety in pediatric chronic inflammatory disease
(2021-05-26)
inflammatory bowel disease (IBD). We found that azathioprine was associated with a 6-fold increased risk of acute pancreatitis during the first 90 days following treatment initiation, compared to no use, based on a sample of 8725 patients (n=3574 azathioprine...
Cysteine biosynthesis in Mycobacterium tuberculosis as potential drug target
(2017-04-20)
The bacterium Mycobacterium tuberculosis is the underlying cause of tuberculosis, one of the most devastating infectious diseases, causing 1.4 million deaths in 2015. In addition one third of the global population is ...
Executive functions and successful behavior
(2021-07-28)
Executive functions are the underlying mechanisms that drive top-down regulation of information processing. While suboptimal executive functions have been investigated in various groups of patients, their impact and ...
Cognitive deficits in alcohol use disorder : etiology and treatment
(2019-11-04)
Alcohol use disorder (AUD) is a psychiatric disorder characterized by a loss of control over drinking, tolerance, withdrawal and negative psychological, physical and social consequences due to excessive alcohol consumption. ...
Coronary prevention in two European areas with different risk levels, Stockholm and Sicily : doctors' risk judgments and statin utilization
(2014-04-24)
Introduction: International guidelines on the primary prevention of cardiovascular disease recommend that preventive measures should be based on the doctors’ quantitative total risk assessment of the patient. Treatment is ...