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Progressive stroke : clinical course and outcome
(1997-05-20)
The knowledge about progression of symptoms in acute stroke patients was scanty when this thesis was planned. The aim was therefore to study if the rate and type of progression, had any impact on patient outcome, predictors ...
Human papillomavirus and cervical carcinoma in situ : implications for future screening
(2000-08-11)
carcinoma in situ was between 7 and 12 years. Among cases, we found a consistently increased load of HPV 16, detected already 13 years before diagnosis, and often when the smear was still cytologically normal. Women with a high load of HPV 16, were...
Physiological status of bacteria used for environmental applications
(2006-12-22)
Several bacteria have properties of interest for biotechnological
applications, such as bioremediation of pollutants and biocontrol of
plant pathogens. In order to perform their intended tasks in the
environment the cells ...
Surfactant treatment in neonatal group B streptococcal pneumonia : experimental and clinical studies
(1999-10-06)
Surfactant dysfunction is probably involved in the pathophysiology of neonatal group B streptococcal (GBS) pneumonia. Aim of the present studies was to evaluate efficacy and safety of surfactant replacement therapy for ...
Rheumatoid arthritis : pharmacological modulation of cytokines : aspects of clinical response and endocrine regulation
(2006-01-06)
Rheumatoid arthritis (RA) is a systemic inflammatory disease primarily affecting the joints. In the pathogenesis several cells of the immune systeme and messengers of the immune systeme, cytokines, are important. In this ...
Pituitary regulation of plasma lipoprotein metabolism and intestinal cholesterol absorption
(2005-11-18)
severely altered basal cholesterol metabolism (increased LDL-C, reduced HDL-C, suppressed LDLR and cholesterol 7alphahydroxylase, CYP7A1), concomitant with a striking loss of resistance to dietary cholesterol. Growth hormone (GH) substitution partly...
Consequences of outsourcing referrals for magnetic resonance examinations
(2012-11-22)
Background: Rapid developments in imaging technology affecting its day-to-day clinical use continue to increase the workload in diagnostic radiology. Along with demands for ever more effective healthcare, these are two ...
Function, expression and polymorphism of human alcohol dehydrogenase 3/glutathionedependent formaldehyde dehydrogenase
(2001-05-02)
Alcohol dehydrogenase 3 (ADH3), identical to glutathione-dependent formaldehyde dehydrogenase, plays a vital role in the defense against formaldehyde through the activity for the spontaneously formed adduct between ...
Pathophysiological characterization of traumatic brain injury using novel analytical methods
(2023-05-02)
clusters and trajectories showed clear outcome differences, with mortality from 7 to 40% in the admission clusters and 4 to 85% in the trajectories. Adding cluster or trajectory labels to the established outcome prediction IMPACT model significantly...
A 10-year follow-up of people with multiple sclerosis-aspects of disability and health, use of and satisfaction with care, and feasibility of cognitive behavioural therapy
(2014-11-21)
Background: Multiple sclerosis (MS) is a neuroinflammatory and neurodegenerative disease in the central nervous system which affects a number of life areas of the afflicted individual. Detailed knowledge is required on ...