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Synaptic vesicle endocytosis studied in a living synapse
(2000-09-29)
Neurons in the central nervous system communicate by transmitting electrical signals at special sites of contact called synapses. Synapses contain neurotransmitter-filled synaptic vesicles, which fuse with the presynaptic ...
Hereditary factors in endometrial cancer
(2015-02-03)
Endometrial carcinoma (EC) is the most common gynecological malignancy in Sweden and accounts for about 6 % of all female malignancies. The risk of EC increases with age and the majority of cases are diagnosed between age ...
Fat mass, adipokines and clinical complications of chronic kidney disease
(2006-05-26)
Patients with chronic kidney disease (CKD), irrespective of initial etiology, have a risk of cardiovascular morbidity (CVD) and mortality that is many-fold higher than that of a similar person without CKD. While traditional ...
Defining the role of migratory dendritic cells in priming T cells to mycobacteria
(2022-05-16)
Dendritic cells (DCs) are professional antigen-presenting cells that bridge innate and adaptive immunity by priming T cells. DCs residing at body surfaces such as skin sense invading microbes and respond by internalizing ...
Clinical studies of glucose variability and hypoglycemia in adult patients with type 1 diabetes
(2011-11-02)
values. The prevalence of complications increased over time from 1990 to 2001. The prevalence of neuropathy increased from 29% to 47%. Statistical analysis showed that HbA1c was an independent predictor of the incidence (p = 0.004) and the prevalence (p...
Molecular epidemiology of tuberculosis
(2011-11-09)
Tuberculosis is a global epidemic, with one third of the world’s population estimated to be infected, around 9 million new active cases per year and close to 2 million deaths per year. Without adequate chemotherapy ...
Molecular mechanisms in synaptic vesicle recycling
(2010-09-03)
Neurons communicate through specialized contacts called synapses, which consist of pre- and postsynaptic compartments separated by a narrow synaptic cleft. The stimulus- dependent rapid influx of calcium ions into the ...
High-sensitivity cardiac troponin T in the emergency department : admissions, resource utilization and outcomes
(2017-05-18)
Background: Patients presenting with chest pain in the emergency department (ED) may have myocardial infarction (MI) requiring immediate treatment. High-sensitivity cardiac troponin T (hs-cTnT) was recently introduced as ...
Signalling pathways controlling bacterial adaptation
(2009-03-27)
The conversion of environmental signals into cellular responses is a critically important process that occurs in all organisms. The ability to process information depends, in general, on complex signal transduction and ...
Investigating the role of p73 proteins in controlling the tumor microenvironment
(2020-10-20)
Cancer is a multifactorial disease governed by oncogenes and tumor suppressors that not only impact on the behavior of the cancer cells but also influence many processes in the surrounding tumor microenvironment. The most ...