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On the control of the microflora in the gastro intestinal tract : functional examples of antibacterial peptides from Helicobacter pylori and mouse small intestine
(2000-09-08)
The human microflora contains at least 400 different species mainly localized to the gastro-intestinal tract. This indigenous flora is controlled by host factors as well as by the interference within the microbial community ...
Epidemiology, risk and protective factors of self-immolation : a study from Iran
(2013-04-04)
Background: Suicide by self-burning (self-immolation) is one of the suicide methods that is far more common in low-middle income countries than in high-income ones. Iran is one of the countries that has a high rate of ...
Insulin signalling and TBC1D1 in skeletal muscle metabolism
(2011-11-18)
in insulin signalling and metabolism. We provide evidence that the TBC1D1-deficient congenic B6.SJL- Nob1.10 (SJL/SJL) mice have enhanced suppression of hepatic glucose production during the euglycemic-hyperinsulinemic clamp. Moreover, glucose uptake...
Studies on ribonucleotide reductase, a target for anticancer therapy, with focus on electron donor aspects : thioredoxin and glutaredoxin systems
(2009-03-27)
Faithful replication of DNA and its repair are fundamental processes in
all living cells which utilize deoxyribonucleotides as DNA building
blocks. Ribonucleotide reductase (RNR) is the essential enzyme for de
novo ...
Getting in and out of shape : relevance for organ formation and cancer
(2014-09-11)
A central question during development is how single cells form functional multi-cellular organ structures. The high reproducibility indicates intricate synchronization of cellular behaviors such as migration, proliferation ...
Outcome of gastric cancer surgery in Sweden
(2020-05-20)
Gastric cancer worldwide is the fifth most common cancer and has the third highest cancer related mortality. Curative treatment includes surgical resection but comes with risk of complications and the optimal surgery ...
High-sensitivity cardiac troponin T in the emergency department : admissions, resource utilization and outcomes
(2017-05-18)
Background: Patients presenting with chest pain in the emergency department (ED) may have myocardial infarction (MI) requiring immediate treatment. High-sensitivity cardiac troponin T (hs-cTnT) was recently introduced as ...
Helicobacter pylori infection among children in Sweden
(2001-04-06)
Since Helicobacter pylori was first identified in 1983 convincing data has linked the infection to the development of gastritis and peptic ulcer disease and H. pylori has further been implicated in gastric carcinogenesis. ...
Novel approaches for cancer immunotherapy
(2008-05-22)
Cancer immunotherapy, i.e. activation of the patient s own immune system to combat cancer, represents a treatment strategy which is being clinically tested to complement surgery, radiotherapy and chemotherapy the current ...
Preoperative radiotherapy in rectal cancer : aspects on fractionation and timing of surgery
(2019-04-30)
of the courses with 5 Gy x 5 were pooled and analysed in a short course RT comparison. About 6 -7 % of the patients with a delay to surgery required hospitalisation between start of RT and surgery due to RT-induced toxicity. In total, 25 patients had a LR within...