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Mortality and psychiatric morbidity among drug addicts in Stockholm
(1997-11-11)
Aim: The aim of the thesis was to assess overall mortality and cause-specific mortality among drug addicts in Stockholm and also to study the relationship between cannabis and psychiatric morbidity and mortality.
Methods: ...
Mithochondrial function in human skeletal muscle : with special reference to exercise and training
(2000-09-15)
The overall objective of this thesis was to study the adaptation of oxidative function in human skeletal muscle to acute exercise of different modes, intensities and durations, and to endurance training.
The effects ...
Regulatory networks of c-di-GMP signalling involved in biofilm formation, motility and host pathogen interactions in Salmonella typhimurium
(2013-08-09)
phosphodiesterase STM4264 targets a global pool of c-di-GMP to inhibit rdar morphotype formation and CsgD expression whereas the GGDEF-EAL phosphodiesterase STM1703 is hypothesized to act locally to inhibit rdar morphotype formation and CsgD expression in S...
Focal spasticity therapy : effects on motor function, health related quality of life, and central nervous system plasticity
(2009-05-21)
, II, IV) we found an overall improvement in motor functions in 88-90% of patients therapeutic targets. Spasticty improved 1.1-1.2 on the Ashworth Scale. Quality of life (study II, n=41) improved in three of the eight SF-36 health scales, of which two...
Mortality and co-morbidity among patients with hemochromatosis and their first-degree relatives
(2010-05-14)
Genetic hemochromatosis (GH) is an autosomal recessive disease caused by
a C282Y mutation in the HFEgene, and is characterized by excess iron
accumulation in multiple organs. Classical manifestations of GH include
liver ...
Co-operation in vocational rehabilitation : methods in multiprofessional cross-sector group meetings and effects on employment
(2008-08-21)
The overall aim of the thesis was to acquire an increased knowledge of
co-operation between different rehabilitation actors in the provision of
vocational rehabilitation (VR). One aim was to investigate the
differences ...
Integrative omics data analysis to discover novel signatures in complex diseases
(2023-03-09)
Apart from diseases caused by the defect of a single gene, most diseases are highly complex and are usually caused by a combination of biological and environmental factors. In the biological context, cellular processes are ...
Human salmonellosis : impact of travel and trade from a Swedish perspective
(2006-09-08)
Background: Salmonellosis is one of the most important gastrointestinal infections in humans. The vast majority of Swedish Salmonella cases have acquired the disease abroad, reflecting both a large number of Swedish ...
Effect of cycline-dependent kinase and matrix metalloproteinase inhibitors on hematopoietic and leukemic cells
(2008-10-24)
Rapid advances in molecular and cellular biology have improved the understanding of the mechanisms involved in leukemia development. Cyclin-dependent kinases (CDKs) and matrix metalloproteinases (MMPs) have been suggested ...
Regulation of biofilm formation in Salmonella typhimurium and Escherichia coli Nissle 1917
(2010-12-20)
in the timing of type 1 versus curli fimbriae surface attachment....