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Drunk driving : a study of psychosocial, and health factors, focusing on young and middle-aged men in a metropolitan area
(1999-11-12)
Drunk driving is a common and serious alcohol-related problem in Sweden and many other countries. In Sweden 9,433 persons, of whom 90 % were men, were convicted of drunk driving in 1997. Surveys indicate that many more ...
Functional and bioinformatical studies of the TGFb superfamily : identification and characterization of ALK7
(2001-11-02)
The transforming growth factor beta (TGFbeta) superfamily of polypeptide
growth factors encompasses more than 30 diverse mammalian members. They
are involved in most cellular processes, ranging from cell proliferation
and ...
Time resolved functional brain networks : a novel method and developmental perspective
(2022-01-28)
Functional neuroimaging has helped elucidating the complexity of brain function in ever more detail during the last 30 years. In this time the concepts used to understand how the brain works has also developed from a focus ...
Mortality and co-morbidity among patients with hemochromatosis and their first-degree relatives
(2010-05-14)
Genetic hemochromatosis (GH) is an autosomal recessive disease caused by
a C282Y mutation in the HFEgene, and is characterized by excess iron
accumulation in multiple organs. Classical manifestations of GH include
liver ...
Regulation of cellular responses to hypoxia by HIF-1alpha-dependent and -independent signaling pathways
(2012-08-13)
of the Hes1 promoter are critical for hypoxia-inducible transcriptional regulation of Hes1 promoter activity. In paper III, we investigated the molecular mechanism of β-cell death triggered by hypoxia. We show that apoptosis induced by exposure to 1% O2...
Towards personalized immunotherapy : development of in vitro models for imaging natural killer cell behavior in the tumor microenvironment
(2022-01-27)
Tremendous advances in the tumor immunology field have transformed immunotherapy from a promising approach to a standard clinical practice. However, a subset of cancer patients is non-responsive to immunotherapy. More ...