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Immune responses related to protection against rotavirus after natural infection and vaccination
(1999-11-19)
with an acute rotavirus infection, serum IgA antibodies were detected against VP2, VP4, VP6, VP7, NSP2, and/or NSP3. Serum IgA antibodies purified from rotavirus seropositive individuals were shown in vitro to neutralize unattached and attached rotavirus. A...
Understanding cellular and cytoskeletal dysregulation in immunodeficiency diseases
(2019-12-18)
The immune system is a complex network of cells and molecules interacting to preserve the integrity and survival of the host by distinguishing self from non-self, and dysregulation of immune cells can lead to immunodeficiency, ...
Integrated assessment of environmental and human health risks of antibiotic residues and resistance for environmental and health policy
(2021-04-27)
Background: Antibiotic resistance is a global health crisis and a serious threat to progress in achieving the Sustainable Development Goals. This requires a One Health response that recognises the link between human and ...
Intrauterine immunology in allergy and infection
(2009-01-02)
investigated different factors in the placenta in relation to chorioamnionitis. In the first study, we investigated TLR2 expression. We demonstrated that expression of TLR2 was lower in placentas with chorioamnionitis compared to healthy placentas...
Misoprostol as a family planning drug : use in pregnant and non-pregnant women
(2014-10-28)
Background: Availability of comprehensive family planning services is fundamental in improving and ensuring women’s right to life and health. An estimated 222 million women have an unmet need for contraception, and 43.8 ...
Avidity-guided radionuclide therapy for thyroid cancer
(2022-09-01)
The treatment of differentiated thyroid cancer has three main modalities: surgery, hormone suppression and radioiodine therapy. Effective radioiodine therapy requires cancer cells to be iodine avid, i.e. exhibit relatively ...
Brain function and behaviour related to development and training of working memory
(2005-10-28)
Training of working memory (WM) is a research field that could result in
new therapeutic breakthroughs for people with impaired WM functions. In
support of this view, research in our group has previously shown that ...
Trajectory mapping of human embryonic stem cell cardiogenesis reveals lineage branch points and an ISL1 progenitor-derived cardiac fibroblast lineage
(2021-02-17)
A family of multipotent heart progenitors plays a central role in the generation of diverse myogenic and nonmyogenic lineages in the heart. Cardiac progenitors in particular play a significant role in lineages involved in ...
Linking quantitative radiology to molecular mechanism for improved vascular disease therapy selection and follow-up
(2022-09-08)
Objective: Therapeutic advancements in atherosclerotic cardiovascular disease have improved the prevention of ischemic stroke and myocardial infarction. However, diagnostic methods for atherosclerotic plaque phenotyping ...