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Isthmic spondylolisthesis in adults : a randomized controlled trial
(1999-11-19)
years (range 18-55). The level of the slip was L5 in 94 patients, L4 in 14 patients and both L4 and L5 in 3 patients. There were 67 patients with a grade I slip, 42 with a grade II slip and 2 with a grade III slip. The patients were randomly allocated...
On the role of metabotropic glutamate receptors in motor control : analysis of synaptic, cellular and network properties
(2000-10-06)
The organization of neurons into neuronal networks is a basic feature of the central nervous system. An understanding of the function of neuronal networks requires knowledge on both synaptic connectivity and cellular ...
Survival after different forms of bystander cardiopulmonary resuscitation in out-of-hospital cardiac arrest : ‛to breathe or not to breathe?’
(2019-10-31)
.5 % for patients receiving CPR and 4.0 % when CPR was not performed, odds ratio (OR) 2.80 (95% CI, 2.47 – 3.18), adjusted OR 2.15 (95 % CI, 1.88 – 2.45). The association with survival was greater when the time to the initiation of CPR was short. In Study II we...
Epstein-Barr virus and genomic instability : a new look at the mechanisms of viral oncogenesis
(2010-12-20)
oxidative stress by transcriptional activation of the catalytic subunit of NADPH oxidise, NOX2. Stable or conditional expression of EBNA1 was associated with the accumulation of telomere abnormalities, including loss and gain of telomere signals, telomere...
Cell cycle and differentiation in Giardia Lamblia
(2008-04-30)
Giardia lamblia is the major cause of waterborne diarrhea worldwide.
Giardiasis is initiated by ingestion of cysts, which after passing
through the stomach are triggered to excyst. Excystation, or awakening
from dormancy, ...
A battle between host and pathogen : the innate immune response and enterovirus evasion strategies
(2014-09-18)
Infections with Coxsackieviruses are common and in most cases the infection is asymptomatic and efficiently cleared. On rare occasions, however, an infection can lead to severe diseases including myocarditis, hepatitis and ...
Neural correlates of individual differences in personality and intelligence : studies using an isochronous timing task and voxel based morphometry
(2009-01-14)
It is easy to imagine that humans have always noticed the differences
between themselves and others and perhaps even speculated about the
origins of these differences. The study of individual differences as a
formal ...
Cardiovascular disease in dementia
(2016-12-08)
The objective of this thesis was to characterize the burden of cardiovascular diseases in patients with dementia, their treatment and association with survival. Further, we aimed to explore whether cardiac structure in ...
Clinical and molecular features of chronic hepatitis C infection and advanced liver disease
(2012-05-16)
interferon (peg-IFN) and ribavirin in 104 patients with HCV-associated Child-Pugh class A liver cirrhosis at a Swedish university clinic. Sustained virological response (SVR) was achieved in 13% of genotype 1-, 60% of genotype 2-, and 31% of genotype 3...
Studies of receptors and modulatory mechanisms in functional responses to cysteinyl-leukotrienes in smooth muscle
(2001-05-18)
Cysteinyl-leukotrienes, i.e. leukotriene (LT) C4, D4 and E4, are inflammatory mediators and potent airway- and vasoconstrictors. Two different cysteinyl-leukotriene receptors have been cloned, CysLT, and CysLT2. The aim of this thesis was to explore...