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Cell cycle control in G1 : restriction points for growth factors and anchorage dependence
(1999-05-07)
through the cell cycle. During G1, the cell decides whether to continue through the cell cycle and divide or exit from the cell cycle to a state of quiescence (G0). Thus, important control mechanisms for cell proliferation and differentiation...
MHC-class I restricted peptide-based immunomodulation of CD8+ T and NK cells
(2012-09-06)
The main aims of the immune system are to protect the host from potential threats by distinguishing self from non-self and altered-self. T cells and NK cells play a key role in the identification and elimination of threats ...
Integrated assessment of environmental and human health risks of antibiotic residues and resistance for environmental and health policy
(2021-04-27)
Background: Antibiotic resistance is a global health crisis and a serious threat to progress in achieving the Sustainable Development Goals. This requires a One Health response that recognises the link between human and ...
Socially dependent avoidance learning : mechanisms of adaptive behavior
(2014-08-08)
Many aspects of human social behavior are likely to be shaped by punishment, threats of punishment, and avoidance of punishment. However, surprisingly little is known about the psychological mechanisms underpinning these ...
Studies on the inflammatory response in experimental acute pyelonephritis and its importance for the development of renal scarring
(2002-01-08)
Acute pyelonephritis especially in childhood is a serious and globally common bacterial infection. The infecting microorganism is often derived from the patient's own bowel flora and mainly affects the renal parenchyma and ...
Customization of tamoxifen therapy : not only a dream
(2011-09-06)
Breast cancer (BC) is the most common form of cancer in western women. The grand majority of the afflicted women are eligible for endocrine treatment. Tamoxifen has been the golden standard treatment for more than three ...
Enhanced recovery after surgery (ERAS) interventions and outcome from colorectal surgery
(2021-01-04)
with shorter LOS (mean 5.6 vs 9.0 days, p < 0.001), lower risk of complications (odds ratio (OR) 0.44, 95 % confidence interval (CI) (0.28 – 0.71)) and symptoms delaying discharge (OR 0.47, 95 % CI (0.32 - 0.70)). The risk of cancer specific death...
Nitric oxide in exhaled gas : studies on physiological regulation and measurements in infants and children
(1999-09-16)
Nitric oxide (NO) is found in the exhaled gas of humans, starting from birth, and is increased in adult patients with bronchial asthma. This study assessed whether the measurement of NO in exhaled gas is technically feasible ...
Alcohol and the effect on some appetite-regulating hormones in man
(2008-11-28)
Beverage containing alcohol has been used for centuries to stimulate appetite. Ingestion of a moderate amount of alcohol increase energy intake. Regulation of food intake is complex. Several factors cooperate such as neural ...
Analysis of phenotype reversibility in Hutchinson-Gilford progeria syndrome in mice
(2017-04-12)
Aging affects all people and is a complex process involving both genetic and environmental factors in a way that is not yet completely understood. Studies of premature aging syndromes might be helpful to acquire further ...