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Blood pressure and dementia in the very old : an epidemiologic study
(1998-03-03)
on October 1, 1987. Of the eligible subjects, 1810 (77%) participated in the initial survey (baseline) in which the Mini-Mental State Examination (MMSE) was used as a screening test for dementia. The Diagnostic and Statistical Manual of Mental Disorders...
Insulin and growth hormone : regulation of adipocyte metabolism during infancy and childhood
(1999-03-30)
rate of lipogenesis early in life is probably important factor for age-dependent expansion of the adipose tissue. The mechanism behind this phenomenon is yet unclear, as there was no variation in the glucose transporter (GLUT1 and GLUT4) expression...
Regulation of mitosis : molecular analysis of the anaphase-promoting complex
(2000-11-10)
cycle regulatory proteins for degradation by the proteasome, thereby allowing progression through the cell cycle. The APC/C is regulated by phosphorylation and by two proteins, Cdc20 and Cdh1, which affect APC/C activity in early mitosis and late mitosis...
Ontogeny of perception of maternal and nosocomial stimuli in infants
(2018-02-27)
Preterm born infants in neonatal units experience unusual sensory inputs that can shape and nurture their developing brains differently from full-term healthy newborn infants. To improve the care of preterm infants and ...
Investigating the role of p73 proteins in controlling the tumor microenvironment
(2020-10-20)
upon loss of ΔNp73, leaving NK cell-mediated killing of tumor cells unaffected. Thirdly, a correlation between high levels of ΔNp73 and HIF-1α protein was observed. We demonstrate that ΔNp73 increases HIF-1α protein stability by interfering...
Plasmodium falciparum response to chloroquine and artemisinin based combination therapy (ACT) in Guinea-Bissau
(2009-11-06)
Plasmodium falciparum causes the most severe form of malaria and is the most common malaria species in sub-Saharan Africa. Chloroquine used to be the most common drug for the treatment of malaria. Due to development of ...
Robot-assisted laparoscopy and sentinel node biopsy in high risk endometrial cancer
(2018-11-15)
for infrarenal paraaortic lymph node count (-1.6, 95% CI -5.78 -2.57). No difference in perioperative complications (Clavien-Dindo classification) or readmissions to hospital within 30 days after surgery was found. RALS was associated with longer operation time...
Early indicators for adverse development of cardiovascular, renal and metabolic function in children born with low birth weight
(2018-08-17)
Prematurity affects more than 10% of infants worldwide and is the main reason for neonatal mortality. Improvements in neonatal care have led to higher survival rates into adulthood. Adverse events during organogenesis and ...
Antibody-associated inflammation in and outside the joint in rheumatoid arthritis
(2017-08-17)
Rheumatoid arthritis (RA) is a systemic autoimmune disease characterized by pain, chronic inflammation and joint destruction. Epidemiological investigations in large populationbased cohorts have identified both genetic (such as HLA-DRB1 Shared...
Preparing midwives as a human resource for maternal health : pre-service education and scope of practice in Gujarat, India
(2014-09-08)
One key strategy to achieve reduction in maternal and neonatal mortality is to scale up the availability of
skilled birth attendants (SBAs). The staff nurses (i.e., registered nurse and midwives) are skilled birth
attendants ...