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Genetic control of myasthenia gravis : a study on cytokine and co-stimulator genes and their related functions
(1999-04-02)
Myasthenia gravis (MG) is a classical autoimmune disease characterised by muscle weakness due to an immune attack against the nicotinic acetylcholine receptor (AchR) on the postsynaptic membrane of the neuromuscular junction. ...
Toxicity of metal and metal oxide nanoparticles : the importance of physicochemical properties and cellular uptake
(2012-10-04)
The use of nanoparticles holds great promises in many technical as well as medical applications. However, development of new technologies, such as nanotechnology, is connected with uncertainties and risks. The same properties ...
Studies on the inflammatory response in experimental acute pyelonephritis and its importance for the development of renal scarring
(2002-01-08)
Acute pyelonephritis especially in childhood is a serious and globally common bacterial infection. The infecting microorganism is often derived from the patient's own bowel flora and mainly affects the renal parenchyma and ...
Diagnosis and treatment of Helicobacter pylori infection in Vietnamese children
(2009-11-20)
regimens, respectively. The overall resistance to clarithromycin, metronidazole and amoxicillin was 50.9%, 65.3% and 0.5%, respectively. In LAC regimen, eradication was linked to the strains being sensitive (OR 7.23, 95% CI 2.10-24.9, relative to resistant...
Toxicity and biocompatibility of nanoparticles, and studies on oxidative stress and DNA damage
(2015-05-11)
Oxidative stress is associated with several diseases, either as a cause or a consequence.
Chronic kidney disease (CKD) is one example of a disease in which elevated levels of
oxidative stress are frequently reported. ...
Cost analysis and policy implications in psychiatric care
(2009-04-01)
in Sweden in 2001 (Study I) was estimated at MSEK 85 774 (M€ 9 426, €1= SEK9.1). Indirect costs were totally predominant and constituted about 80% of the total cost, i.e. production losses due to early retirement, sickness absence and premature death...
Determination of transcription factor binding specificities
(2015-11-19)
The term "genetic code" refers to the way in which the information encoded in nucleic acids
is converted into the amino-acid sequence of proteins. There is however also a second genetic
code, one that is used by the cells ...
Understanding cellular and cytoskeletal dysregulation in immunodeficiency diseases
(2019-12-18)
The immune system is a complex network of cells and molecules interacting to preserve the integrity and survival of the host by distinguishing self from non-self, and dysregulation of immune cells can lead to immunodeficiency, ...
Integrated assessment of environmental and human health risks of antibiotic residues and resistance for environmental and health policy
(2021-04-27)
Background: Antibiotic resistance is a global health crisis and a serious threat to progress in achieving the Sustainable Development Goals. This requires a One Health response that recognises the link between human and ...
Influenza specific T- and B-cell responses in immunosuppressed patients
(2015-04-15)
Influenza, known as the ‘flu’, is a recurrent acute viral infection that might cause severe inflammation, particularly in vulnerable individuals, i.e. young children, the elderly, and immune-suppressed patients, such as ...