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Transcription factors regulating the immunoglobulin heavy chain locus
(1999-05-21)
The immunoglobulin heavy (IgH) chain locus is subject to somatic recombination and changes in gene expression in B lineage cells. Enhancers located in the 3' end of the locus may in part regulate these events. This work ...
Acute lung injury : incidence and predictors of outcome with special reference to inhaled nitric oxide
(1999-04-16)
) treated with INO in Scandinavia 1991-1994. Survivors (n=16) were tested with pulmonary function tests > 8 months after the acute episode. To assess genotoxicity, ten healthy volunteers were exposed for INO with scoring of chromosome aberrations...
Early supported hospital discharge and continued rehabilitation at home after stroke
(2000-03-17)
This thesis, based on studies conducted in the South West Health District of Stockholm County sought: 1) to explore and compare the behavior of patients and therapists during stroke rehabilitation sessions in the home and ...
Functional and bioinformatical studies of the TGFb superfamily : identification and characterization of ALK7
(2001-11-02)
The transforming growth factor beta (TGFbeta) superfamily of polypeptide
growth factors encompasses more than 30 diverse mammalian members. They
are involved in most cellular processes, ranging from cell proliferation
and ...
Cardiovascular development of the preterm infant
(2016-09-16)
The numbers of preterm births and cardiovascular deaths are increasing in most countries. The causes of both developments are multiple and apparently not related to each other. However, preterm birth might provide an ...
The study of sensory cilia development in Caenorhabditis elegans
(2008-01-04)
Cilia and flagella are widespread eukaryotic subcellular components
that are conserved from green algae to mammals. In different organisms
they function in cell motility, movement of extracellular fluids and
sensory ...
Impact of infertility and assisted reproductive technology on cancer risk
(2018-05-07)
Ovarian stimulation drugs, in particular those used in assisted reproductive technology (ART)
treatments for infertility, have been suspected to influence cancer risk. In addition, infertility
per se may be a risk factor ...
Nitric oxide in exhaled gas : studies on physiological regulation and measurements in infants and children
(1999-09-16)
Nitric oxide (NO) is found in the exhaled gas of humans, starting from birth, and is increased in adult patients with bronchial asthma. This study assessed whether the measurement of NO in exhaled gas is technically feasible ...
Visualizing the dynamic interplay between the host and bacterial pathogen : a real-time study of renal infection
(2007-05-10)
The human body is a complex entity capable of handling a variety of
pathogenic challenges without developing disease symptoms. Sometimes,
however, the pathogens are superior and the host immune system is unable
to clear ...
CYP2D6-polymorphism and effect of adjuvant tamoxifen in breast cancer patients
(2023-09-04)
Adjuvant tamoxifen at the standard dose of 20 mg daily for five to ten years reduces the risk for relapse and mortality in hormone sensitive breast cancer. The effect however varies and no early marker of poor response is ...