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The diagnosis and protection of the auditory peripheral system
(1999-01-15)
The main focus of this thesis is on the diagnosis and prevention of peripheral hearing loss. An auditory evoked response measure (forward masking) was developed that specifically tests the function of the inner hair cells, ...
Mechanisms for leukocyte-mediated adjustment of endothelial barrier function
(2001-05-09)
on permeable membranes and mounted in a two-compartment diffusion chamber, was utilized to analyze PMN activationinduced effects on endothelial junction integrity. Adding PMN to the upper compartment and a chemotactic stimulus (fMLP or LTB4) to the lower...
Envelopment of retrovirus and vaccinia virus
(2001-08-10)
This thesis describes envelopment of retrovirus and vaccinia virus. Retrovirus envelopment, i.e. budding, occurs from the plasma membrane (PM) of infected cells in an environment that is abundant with cellular proteins. ...
Structural enzymology of oxalate degradation in Oxalobacter formigenes
(2008-01-04)
Oxalic acid, as one of nature's most highly oxidised compounds, is toxic
to most organisms. It is introduced in the human body in the diet but
also as a waste product of cellular metabolism. Mammals do not posses ...
Diabetic osteopathy : a study in the rat
(2012-03-09)
-I was reduced by 18%, while IGFBP-1 and IGFBP-4 were increased by 89 and 20 %, respectively. This complies with the lower BMD in the diabetic rats. In cortical bone, IGF-I was reduced by 38%, whereas no change was seen in ankles. The loss of IGF-I in cortical...
Diagnosis and treatment of Helicobacter pylori infection in Vietnamese children
(2009-11-20)
with eradication rates (OR 8.13, 95% CI 2.23-29.6). These differences were not seen for the LAM regimen. Low age was the most prominent independent risk factor for reinfection (adjusted HR among children aged 3-4, 5-6, and 7-8 years, relative to those aged 9...
Innate regulation of the adaptive immune system during autoimmunity
(2015-05-22)
Immune activation comprises multiple biological checkpoints to ensure proper
and regulated effector functions. Phagocytes such as macrophages, dendritic
cells and neutrophils have important functions during inflammation, ...
Experimental therapeutics against malignant mesothelioma : investigations in vitro
(2009-11-20)
Malignant mesothelioma is a tumour of the mesothelium, a specialized tissue found in the pleura, pericardium, peritoneum, and tunica vaginalis testis. The tumour has strong etiological links to asbestos, with a latency ...
Movement pattern, power generation and well-being in children and young adults with spastic unilateral cerebral palsy
(2011-03-07)
Patients with unilateral cerebral palsy (CP) all walk, most of them without great difficulty and without assistive devices. However, their walk tends to catch the eye because of abnormal, often asymmetrical movement in the ...
Cutaneous leishmaniasis : treatment and genetic mechanisms affecting outcome
(2022-08-25)
Leishmaniasis is a neglected parasitic disease and a rare diagnosis in non-endemic countries in Europe. Migration, geopolitical conflicts and climate change have increased awareness of this infection in Europe, as more ...