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On ionising radiation and breast cancer risk
(1999-01-01)
Background: It is well known that exposure to ionising radiation increases the risk for breast cancer occurrence. However, better understanding of breast cancer risks in terms of dose-response relationships formulated ...
Assisted reproduction technology in men with ejaculatory dysfunction with special reference to spinal cord injury
(1998-05-16)
Background: Men afflicted by spinal cord injury (SCI), myelomeningocele (MMC) and testicular cancer (TC) with retroperitoneal lymph-node dissection (RPLND) share the problem of infertility due mainly, but not exclusively, ...
Cell cycle and differentiation in Giardia Lamblia
(2008-04-30)
Giardia lamblia is the major cause of waterborne diarrhea worldwide.
Giardiasis is initiated by ingestion of cysts, which after passing
through the stomach are triggered to excyst. Excystation, or awakening
from dormancy, ...
Characterisation of CD8 T cells in mucosa associated lymphoid tissue : implications for immune control of HIV-1 infection
(2006-02-24)
to determine the disease relevance of effector and memory cells distinguished by the level of CD7 expression. It was found that CD8 T cells from HIV-1 infected patients display profound down-modulation of CD7 expression as compared to healthy subjects...
Subjective well-being in an adult Swedish population : findings from a population-based study
(2009-01-09)
This doctoral thesis examines various factors associated with subjective
well-being (SWB) in an adult Swedish population, aged 20-64 years, using
cross-sectional and longitudinal data. The thesis includes four studies
based ...
Antenatal corticosteroid exposure : studies on neonatal and long term outcome
(2017-10-23)
for preterm delivery to reduce the risk of respiratory distress syndrome (RDS) and death of her preterm infant. The protective effect of ACS declines after 7-10 days. Considering that up to 50% of women remain undelivered 7-10 days after ACS administration...
Epidemiological studies of suicide : classification bias, drug use, and social circumstances
(2013-04-12)
with SSRI with an odds ratio (OR) of 3.7 [95% CI: 2.8-4.9]. Induction time analyses showed the overall highest risk during days 8-11 after SSRI initiation with an overall OR of 9.7 [2.9-31.7]. Regardless of causation issues our findings deserve further...
Platelet function in diabetes mellitus : relationships to hyperglycaemia, antidiabetic treatment and microangiopathy
(2005-01-14)
Diabetes mellitus is associated with accelerated atherosclerosis and increased morbidity and mortality in micro-and macrovascular complications. The metabolic derangements that accompany diabetes can adversely influence ...
Development of multi-cellular human lung models to study inflammatory mechanisms and cell-cell interactions
(2018-05-17)
It is well known that exposure to toxicants in the environment is associated with a wide range of health effects. The airway epithelium which forms the first line of defense, plays critical roles in the defence against ...
Molecular insights into Hutchinson-Gilford progeria syndrome and age-associated disease : from mechanisms to treatment strategy
(2019-08-30)
% of the CKD patients arteries (in up to 7.4% of the cells), which was associated with an increase in DNA damage. When searching for the cause of progerin expression, we identified the LMNA c.1824C>T mutation in both the blood and arteries. Our data further...