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Psychosocial factors in trauma patients : studies on trauma recurrence and trauma recovery
(1996-05-21)
The present studies aimed to highlight the influence of psychosocial and psychiatric factors on trauma recurrence and trauma recovery. A subgroup of trauma patients, 820 victims of firearm injuries, were compared to an ...
Asthma during pregnancy in a population-based study : pregnancy complications and adverse perinatal outcomes
(2017-01-02)
BACKGROUND: Asthma is one of the most common chronic diseases, and prevalence,
severity and medication may have an effect on pregnancy. We examined maternal
asthma, asthma severity and control in relation to ...
Emergency department crowding and hospital patient flow : influential factors and evidence-Informed solutions
(2016-09-06)
predicting failure for the 4hr target were: PIAD> 2hrs (OR 15.80 [13.35-18.71]), consultation (OR 20.98 [14.10- 31.22]), TnI (OR 13.37 [6.30-28.37]), MRI (OR 31.68 [6.03-166.54]), or CT (OR 16.48 [10.07-26.98]). Study IV found that the Australian hospital...
Cytoskeleton-interacting proteins in brainstem development : roles of KCC2 and Vangl2
(2010-12-21)
, while these genes act in separate phases of development, they share the common feature of regulating the integrity of the neuronal cytoskeleton necessary for maturation of the brainstem. KCC2 is a neuronal K+/Cl-cotransporter that is responsible...
Integrative omics data analysis to discover novel signatures in complex diseases
(2023-03-09)
Apart from diseases caused by the defect of a single gene, most diseases are highly complex and are usually caused by a combination of biological and environmental factors. In the biological context, cellular processes are ...
Pursuing the fever trail : pathogenesis of blood-stage P. falciparum malaria and pregnancy
(2008-05-19)
The burden of the most virulent form of human malarias, Plasmodium
falciparum, is concentrated among young children and pregnant women in
sub-Saharan Africa. Excessive sequestration of parasite-infected red
blood cells ...
Dysglycaemia and cardiovascular disease. Aspects on screening, management, and prognosis
(2023-03-24)
Background: Dysglycaemia, in this thesis defined as impaired glucose tolerance (IGT) or type 2 diabetes (T2DM), is a major risk factor for cardiovascular disease (CVD). International guidelines recommend screening for dysglycaemia and target...
Regulation of Plasmodium falciparum virulence genes and immune response to surface antigens in placental malaria
(2011-11-15)
. falciparum erythrocyte membrane protein 1 (PfEMP1) VAR2CSA is the main adhesin involved in placental malaria. We investigated the differential recognition of various VAR2CSA DBL-domains by immune sera from pregnant women and found DBL5ε to be widely...
Misoprostol as a family planning drug : use in pregnant and non-pregnant women
(2014-10-28)
Background: Availability of comprehensive family planning services is fundamental in improving and ensuring women’s right to life and health. An estimated 222 million women have an unmet need for contraception, and 43.8 ...
Ultrasound assessment and risk prediction in women with endometrial cancer
(2020-01-09)
by combined endometrial biopsy and ultrasound. Demographic (age ≥ 65 years and waist circumference ≥ 88 cm), sonographic (ultrasound tumor extension and ultrasound AP diameter ≥ 2 cm) and ProMisE variables combined had higher ability to predict recurrence...